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NCT01683071 · ClinicalTrials.gov registry record · Phase 2

Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia Following Total Knee Arthroplasty

A Phase 2 study, sponsored by Pacira Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
297
Enrollment target

NCT01683071 is a Phase 2 study that has completed, run by Pacira Pharmaceuticals. The registered enrollment target is 297 participants.

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The verdict

NCT01683071, a Phase 2 study, has completed, sponsored by Pacira Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
297 participants
Enrollment target

Study Summary

The primary objectives of Part 1 are to (1) evaluate three dose levels of liposome bupivacaine versus placebo with respect to the magnitude and duration of the analgesic effect achieved following single dose injection femoral nerve block with liposome bupivacaine, and (2) select a single therapeutic dose of liposome bupivacaine from the three dose levels to be tested in Part 2. Part 2: The primary objective of Part 2 is to compare the magnitude and duration of the analgesic effect of single injection femoral nerve block of a single dose level of liposome bupivacaine (selected from Part 1) with placebo (preservative-free normal saline).

Interventions

  • DRUG Placebo
  • DRUG EXPAREL 67 mg
  • DRUG EXPAREL 133 mg
  • DRUG EXPAREL 266 mg

Trial Details

FieldValue
Enrollment Target 297 participants
Start Date 2012-09
Est. Completion 2013-12
Phase Phase 2

Sponsor

Pacira Pharmaceuticals

88 total trials

What the Registry Record Tells You About NCT01683071

The ClinicalTrials.gov registry entry for NCT01683071 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 297 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pacira Pharmaceuticals, which has 88 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.

NCT01683071 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01683071 about?

NCT01683071 is a clinical study titled "Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia Following Total Knee Arthroplasty". The primary objectives of Part 1 are to (1) evaluate three dose levels of liposome bupivacaine versus placebo with respect to the magnitude and duration of the analgesic effect achieved following single dose injection femoral nerve block with liposome bupivacaine, and (2) select a single therapeutic...

What is the current status of trial NCT01683071?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 297 participants. The study started on 2012-09. Estimated completion is 2013-12.

What interventions are being tested in trial NCT01683071?

The interventions under investigation include: Placebo (DRUG), EXPAREL 67 mg (DRUG), EXPAREL 133 mg (DRUG), EXPAREL 266 mg (DRUG).

Who is sponsoring clinical trial NCT01683071?

This trial is sponsored by Pacira Pharmaceuticals, which has 88 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.