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NCT01682512 · ClinicalTrials.gov registry record · Phase 3

Efficacy, Pharmacokinetics, and Safety of BI 695500 in Patients With Rheumatoid Arthritis

A Phase 3 study, sponsored by Boehringer Ingelheim.

Terminated
Registry status
Phase 3
Development phase
294
Enrollment target

NCT01682512 is a Phase 3 study that was terminated before completion, run by Boehringer Ingelheim. The registered enrollment target is 294 participants.

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The verdict

NCT01682512, a Phase 3 study, was terminated before completion, sponsored by Boehringer Ingelheim.

TERMINATED
Registry status
Phase 3
Development phase
294 participants
Enrollment target

Study Summary

The primary objectives of this trial are (1) To show PK (Pharmacokinetic) similarity of BI 695500 to rituximab. (2)To establish statistical equivalence of efficacy of BI 695500 and rituximab, in patients with moderately to severely active RA (Rheumatoid Arthritis), based on the change in Disease Activity Score 28 (DAS28) score measured at 24 weeks compared to Baseline and the American College of Rheumatology 20% (ACR20) response rate at Week 24.

Interventions

  • DRUG BI 695500
  • DRUG Rituxan®
  • DRUG MabThera®

Trial Details

FieldValue
Enrollment Target 294 participants
Start Date 2012-09-05
Est. Completion 2016-10-12
Phase Phase 3

Sponsor

Boehringer Ingelheim

515 total trials

What the Registry Record Tells You About NCT01682512

The ClinicalTrials.gov registry entry for NCT01682512 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 294 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boehringer Ingelheim, which has 515 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which BI 695500 is the first listed.

NCT01682512 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01682512 about?

NCT01682512 is a clinical study titled "Efficacy, Pharmacokinetics, and Safety of BI 695500 in Patients With Rheumatoid Arthritis". The primary objectives of this trial are (1) To show PK (Pharmacokinetic) similarity of BI 695500 to rituximab. (2)To establish statistical equivalence of efficacy of BI 695500 and rituximab, in patients with moderately to severely active RA (Rheumatoid Arthritis), based on the change in Disease Act...

What is the current status of trial NCT01682512?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 294 participants. The study started on 2012-09-05. Estimated completion is 2016-10-12.

What interventions are being tested in trial NCT01682512?

The interventions under investigation include: BI 695500 (DRUG), Rituxan® (DRUG), MabThera® (DRUG).

Who is sponsoring clinical trial NCT01682512?

This trial is sponsored by Boehringer Ingelheim, which has 515 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.