Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01649297 · ClinicalTrials.gov registry record · Phase 2

A 16 Weeks Study on Efficacy and Safety of Two Doses of Empagliflozin (BI 10773) (Once Daily Versus Twice Daily) in Patients With Type 2 Diabetes Mellitus and Preexisting Metformin Therapy

A Phase 2 study, sponsored by Boehringer Ingelheim.

Completed
Registry status
Phase 2
Development phase
983
Enrollment target

NCT01649297 is a Phase 2 study that has completed, run by Boehringer Ingelheim. The registered enrollment target is 983 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01649297, a Phase 2 study, has completed, sponsored by Boehringer Ingelheim.

COMPLETED
Registry status
Phase 2
Development phase
983 participants
Enrollment target

Study Summary

The aim of this study is to investigate the efficacy and safety of two doses (high and low) of empagliflozin as add-on therapy to metformin in patients with type 2 diabetes mellitus (T2DM) and insufficient glycaemic control. Both doses may be given once daily or split to a twice daily dosage. This results in 4 different dosage regimens of empagliflozin (high dose once daily or split vs. low dose once daily or split). This is done to evaluate whether a twice daily dose regimen of empagliflozin results in a loss of efficacy relative to once daily dosing when given on top of metformin background therapy.

Interventions

  • DRUG Placebo

Trial Details

FieldValue
Enrollment Target 983 participants
Start Date 2012-10
Est. Completion 2013-12
Phase Phase 2

Sponsor

Boehringer Ingelheim

515 total trials

What the Registry Record Tells You About NCT01649297

The ClinicalTrials.gov registry entry for NCT01649297 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 983 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boehringer Ingelheim, which has 515 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Placebo is the first listed.

NCT01649297 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01649297 about?

NCT01649297 is a clinical study titled "A 16 Weeks Study on Efficacy and Safety of Two Doses of Empagliflozin (BI 10773) (Once Daily Versus Twice Daily) in Patients With Type 2 Diabetes Mellitus and Preexisting Metformin Therapy". The aim of this study is to investigate the efficacy and safety of two doses (high and low) of empagliflozin as add-on therapy to metformin in patients with type 2 diabetes mellitus (T2DM) and insufficient glycaemic control. Both doses may be given once daily or split to a twice daily dosage. This r...

What is the current status of trial NCT01649297?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 983 participants. The study started on 2012-10. Estimated completion is 2013-12.

What interventions are being tested in trial NCT01649297?

The interventions under investigation include: Placebo (DRUG).

Who is sponsoring clinical trial NCT01649297?

This trial is sponsored by Boehringer Ingelheim, which has 515 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.