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NCT01646333 · ClinicalTrials.gov registry record · NA
A Trial of Neurocognitive and Supportive Therapy Interventions for Individuals With Parkinson's Disease
A NA study of Mild Cognitive Impairment and Parkinson's Disease, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- NA
- Development phase
- 32
- Enrollment target
- 1
- Study location
NCT01646333: Completed NA study of Mild Cognitive Impairment and Parkinson's Disease, sponsored by Virginia Commonwealth University.
NCT01646333 is a NA study of Mild Cognitive Impairment and Parkinson's Disease that has completed, run by Virginia Commonwealth University. The registered enrollment target is 32 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01646333, a NA study of Mild Cognitive Impairment and Parkinson's Disease, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
- 1
- Study location
Study Summary
This randomized, controlled trial (RCT) evaluates the benefits of memory and problem solving training compared to supportive therapy in individuals with Parkinson's Disease with Mild Cognitive Impairment (MCI) and their support persons. Participants will be randomly assigned to receive memory and problem solving training or supportive therapy for 2-months. A 6-month follow up evaluation will establish if benefits remain over time. Impact of these therapies on thinking abilities, physical health, and patient and support person ratings of thinking skills, mood and quality of life will be evaluated. The memory and problem solving training is hypothesized to result in greater improvements and/or stability of function on neuropsychological tests of attention, working memory, learning, and memory skills compared to the supportive therapy condition. Both conditions are hypothesized to result in improved mood and quality of life ratings. Results from this study will determine whether memory and problem solving therapies and supportive therapy are easily used by and beneficial for individuals with Parkinson's Disease and Mild Cognitive Impairment. If positive benefit is observed, information from this study will be used to further optimize these therapies for larger trials designed to evaluate the value of the therapies for individuals with Parkinson's Disease and their support persons.
Primary Outcome
Change in California Verbal Learning Test-II Long Delay Free Recall Scaled Score from Baseline and 10 weeks
Conditions Studied
Interventions
- BEHAVIORAL Supportive Therapy
- BEHAVIORAL Memory and Problem-Solving Intervention
Study Locations (1)
Virginia
- VCU Parkinson's and Movement Disorders Center - Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2012-07 |
| Est. Completion | 2015-12 |
| Phase | NA |
What the finished NCT01646333 record still lists
NCT01646333 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 2 interventions - of which Supportive Therapy is the first listed.
NCT01646333 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT01646333 about?
NCT01646333 is a clinical study titled "A Trial of Neurocognitive and Supportive Therapy Interventions for Individuals With Parkinson's Disease". This randomized, controlled trial (RCT) evaluates the benefits of memory and problem solving training compared to supportive therapy in individuals with Parkinson's Disease with Mild Cognitive Impairment (MCI) and their support persons. Participants will be randomly assigned to receive memory and pr...
What is the current status of trial NCT01646333?
This trial is currently completed. It is a NA study. The enrollment target is 32 participants. The study started on 2012-07. Estimated completion is 2015-12.
What conditions does trial NCT01646333 study?
This clinical trial studies the following conditions: Mild Cognitive Impairment, Parkinson's Disease.
What interventions are being tested in trial NCT01646333?
The interventions under investigation include: Supportive Therapy (BEHAVIORAL), Memory and Problem-Solving Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT01646333?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01646333 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01646333's enrollment target sits among peer trials
32 163rd of 205 higher than 42 of 205 other Mild Cognitive Impairment trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Mild Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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