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NCT01640158 · ClinicalTrials.gov registry record · NA

Broad-spectrum Cognitive Remediation: Effects of a Brain Plasticity-based Program in Mild Traumatic Brain Injury

A NA study of Traumatic Brain Injury, sponsored by Posit Science Corporation.

Completed
Registry status
NA
Development phase
86
Enrollment target
1
Study location

NCT01640158: Completed NA study of Traumatic Brain Injury, sponsored by Posit Science Corporation.

NCT01640158 is a NA study of Traumatic Brain Injury that has completed, run by Posit Science Corporation. The registered enrollment target is 86 participants, below the 277-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01640158, a NA study of Traumatic Brain Injury, has completed, sponsored by Posit Science Corporation.

COMPLETED
Registry status
NA
Development phase
86 participants
Enrollment target
1
Study location

Study Summary

The primary objective of this study is to evaluate the effects of plasticity-based, adaptive cognitive remediation on the cognitive abilities, functional status and quality of life of soldiers and veterans diagnosed with persistent post-concussive symptoms (PPCS) following a mild traumatic brain injury (mTBI, also referred to as a concussion, or blast exposure), as compared to a computer-based control.

Primary Outcome

Between-group magnitude of change in composite score with the measure constructed from Rey Auditory Verbal Learning Test (RAVLT) sum of trials 1-5 (immediate verbal memory), RAVLT delayed verbal recall, the Ruff Light Trails Test (RULIT) sum of trials 2-10 (immediate visual memory), RULIT delayed recall scores, digit span (WAIS, sum of forwards, backwards, sequencing), symbol span (WMS), anti-saccades, flanker, and set-shifting (each from the EXAMINER battery).

Conditions Studied

Interventions

  • OTHER Commercially available computerized training
  • OTHER Computerized Plasticity-based Adaptive Cognitive Training

Study Locations (1)

California

  • Posit Science Corporation - San Francisco

Trial Details

FieldValue
Enrollment Target 86 participants
Start Date 2013-09
Est. Completion 2017-03-02
Phase NA
Posit Science Corporation

30 total trials

What the finished NCT01640158 record still lists

NCT01640158 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 86 participants, a relatively small participant target, below the 277-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (69% lower).

The record links to 1 condition, with Traumatic Brain Injury appearing as the primary indexed condition, and to 2 interventions - of which Commercially available computerized training is the first listed.

NCT01640158 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT01640158 about?

NCT01640158 is a clinical study titled "Broad-spectrum Cognitive Remediation: Effects of a Brain Plasticity-based Program in Mild Traumatic Brain Injury". The primary objective of this study is to evaluate the effects of plasticity-based, adaptive cognitive remediation on the cognitive abilities, functional status and quality of life of soldiers and veterans diagnosed with persistent post-concussive symptoms (PPCS) following a mild traumatic brain inj...

What is the current status of trial NCT01640158?

This trial is currently completed. It is a NA study. The enrollment target is 86 participants. The study started on 2013-09. Estimated completion is 2017-03-02.

What conditions does trial NCT01640158 study?

This clinical trial studies the following conditions: Traumatic Brain Injury.

What interventions are being tested in trial NCT01640158?

The interventions under investigation include: Commercially available computerized training (OTHER), Computerized Plasticity-based Adaptive Cognitive Training (OTHER).

Who is sponsoring clinical trial NCT01640158?

This trial is sponsored by Posit Science Corporation, which has 30 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01640158 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Traumatic Brain Injury

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01640158's enrollment target sits among peer trials

86 82nd of 171 higher than 90 of 171 other Traumatic Brain Injury trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Traumatic Brain Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01640158, the US trial registry maintained by the National Library of Medicine. NCT01640158 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.