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NCT01627587 · ClinicalTrials.gov registry record · Phase 1

A Two Cohort Study to Look at the Metabolites of GSK221149, the Metabolism of GSK221149 Administered With a High Fat Meal and With Ketoconazole

A Phase 1 study of Obstetric Labour, Premature, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 1
Development phase
46
Enrollment target
1
Study location

NCT01627587 is a Phase 1 study of Obstetric Labour, Premature that has completed, run by GlaxoSmithKline. The registered enrollment target is 46 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT01627587, a Phase 1 study of Obstetric Labour, Premature, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 1
Development phase
46 participants
Enrollment target
1
Study location

Study Summary

This is a two part study. Part A of the study will evaluate the metabolites of GSK221149 following single and repeat oral dosing and will also assess the pharmacokinetics of GSK221149 when administered with a potent CYP3A4 inhibitor Ketoconazole. Part B of the study will look at the pharmacokinetics of GSK221149 following a high fat meal.

Interventions

  • DRUG Ketoconazole
  • DRUG GSK221149 750 mg
  • DRUG GSK221149 100 mg
  • DRUG GSK221149 750 mg Fasted
  • DRUG GSK221149 750 mg + Food

Study Locations (1)

Texas

  • GSK Investigational Site - Austin

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 2011-12-12
Est. Completion 2012-02-09
Phase Phase 1

Sponsor

GlaxoSmithKline

1,345 total trials

What the Registry Record Tells You About NCT01627587

The ClinicalTrials.gov registry entry for NCT01627587 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 46 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 1,345 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Obstetric Labour, Premature appearing as the primary indexed condition, and to 5 interventions - of which Ketoconazole is the first listed.

NCT01627587 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT01627587 about?

NCT01627587 is a clinical study titled "A Two Cohort Study to Look at the Metabolites of GSK221149, the Metabolism of GSK221149 Administered With a High Fat Meal and With Ketoconazole". This is a two part study. Part A of the study will evaluate the metabolites of GSK221149 following single and repeat oral dosing and will also assess the pharmacokinetics of GSK221149 when administered with a potent CYP3A4 inhibitor Ketoconazole. Part B of the study will look at the pharmacokinetics...

What is the current status of trial NCT01627587?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 46 participants. The study started on 2011-12-12. Estimated completion is 2012-02-09.

What conditions does trial NCT01627587 study?

This clinical trial studies the following conditions: Obstetric Labour, Premature.

What interventions are being tested in trial NCT01627587?

The interventions under investigation include: Ketoconazole (DRUG), GSK221149 750 mg (DRUG), GSK221149 100 mg (DRUG), GSK221149 750 mg Fasted (DRUG), GSK221149 750 mg + Food (DRUG).

Who is sponsoring clinical trial NCT01627587?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01627587 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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