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NCT05674656 · ClinicalTrials.gov registry record · Phase 1

Pharmacokinetics, Safety, Tolerability of Dolutegravir/Rilpivirine in Pediatrics

A Phase 1 study of HIV Infections, sponsored by ViiV Healthcare.

Recruiting
Registry status
Phase 1
Development phase
20
Enrollment target
8
Study locations

NCT05674656 is a Phase 1 study of HIV Infections that is actively recruiting participants, run by ViiV Healthcare. The registered enrollment target is 20 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (96% lower). The trial reports 8 study locations across 5 states.

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The verdict

NCT05674656, a Phase 1 study of HIV Infections, is actively recruiting participants, sponsored by ViiV Healthcare.

RECRUITING
Registry status
Phase 1
Development phase
20 participants
Enrollment target
8
Study locations

Study Summary

The purpose of this study is to provide data on the pharmacokinetic (PK), safety, tolerability, efficacy and acceptability of this fixed dose combination (FDC) single tablet 2-drug regimen for virologically suppressed (HIV-1 RNA \[Ribonucleic Acid\] \< 50 \[cells per milliliter\] c/mL) children 6 to less than 12 years of age, weighing at least 25 kilogram (kg).

Conditions Studied

Interventions

  • DRUG Dolutegravir/Rilpivirine FDC

Study Locations (8)

Florida

  • GSK Investigational Site - Fort Lauderdale
  • GSK Investigational Site - Miami
  • GSK Investigational Site - Tampa

Texas

  • GSK Investigational Site - Houston
  • GSK Investigational Site - Houston

California

  • GSK Investigational Site - Long Beach

District of Columbia

  • GSK Investigational Site - Washington D.C.

Georgia

  • GSK Investigational Site - Atlanta

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2023-07-06
Est. Completion 2028-05-03
Phase Phase 1

Sponsor

ViiV Healthcare

182 total trials

What the Registry Record Tells You About NCT05674656

The ClinicalTrials.gov registry entry for NCT05674656 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (96% lower). The listed sponsor is ViiV Healthcare, which has 182 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which Dolutegravir/Rilpivirine FDC is the first listed.

NCT05674656 reports 8 study locations spanning 5 distinct geographic areas - top geographies include Florida, Texas, California.

Frequently Asked Questions

What is clinical trial NCT05674656 about?

NCT05674656 is a clinical study titled "Pharmacokinetics, Safety, Tolerability of Dolutegravir/Rilpivirine in Pediatrics". The purpose of this study is to provide data on the pharmacokinetic (PK), safety, tolerability, efficacy and acceptability of this fixed dose combination (FDC) single tablet 2-drug regimen for virologically suppressed (HIV-1 RNA \[Ribonucleic Acid\] \< 50 \[cells per milliliter\] c/mL) children 6 to...

What is the current status of trial NCT05674656?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2023-07-06. Estimated completion is 2028-05-03.

What conditions does trial NCT05674656 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT05674656?

The interventions under investigation include: Dolutegravir/Rilpivirine FDC (DRUG).

Who is sponsoring clinical trial NCT05674656?

This trial is sponsored by ViiV Healthcare, which has 182 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05674656 being conducted?

This trial has 8 study locations across California, District of Columbia, Florida, Georgia, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.