Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01563172 · ClinicalTrials.gov registry record · Phase 4
Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride
A Phase 4 study, sponsored by GlaxoSmithKline.
- Completed
- Registry status
- Phase 4
- Development phase
- 65
- Enrollment target
NCT01563172: Completed Phase 4 study, sponsored by GlaxoSmithKline.
NCT01563172 is a Phase 4 study that has completed, run by GlaxoSmithKline. The registered enrollment target is 65 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01563172, a Phase 4 study, has completed, sponsored by GlaxoSmithKline.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 65 participants
- Enrollment target
Study Summary
This study will evaluate and compare the effect of the amount of toothpaste used and brushing time on enamel strengthening (percent of surface microhardness recovery, % SMHR) and enamel fluoride uptake (EFU).
Primary Outcome
SMH recovery test was used to assess the changes in mineralization status of enamel specimens using a Wilson 2100 Hardness tester. SMH recovery was performed in-vitro and determined by measuring the length of the indentations of enamel specimens. An increase in the indentation length compared to the baseline indicates softening while decrease in the indentation length represents re-hardening of enamel surface. % SMH recovery was calculated from indentation length (micrometer \[μm\]) of sound ena
Interventions
- DRUG Sodium fluoride / silica and carbopol, 0.5g
- DRUG Sodium fluoride / silica and carbopol, 1.5g
- OTHER Fluoride free dentifrice
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 65 participants |
| Start Date | 2009-01-01 |
| Est. Completion | 2009-06-01 |
| Phase | Phase 4 |
What the finished NCT01563172 record still lists
NCT01563172 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 3 interventions - of which Sodium fluoride / silica and carbopol, 0.5g is the first listed.
NCT01563172 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01563172 about?
NCT01563172 is a clinical study titled "Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride". This study will evaluate and compare the effect of the amount of toothpaste used and brushing time on enamel strengthening (percent of surface microhardness recovery, % SMHR) and enamel fluoride uptake (EFU).
What is the current status of trial NCT01563172?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 65 participants. The study started on 2009-01-01. Estimated completion is 2009-06-01.
What interventions are being tested in trial NCT01563172?
The interventions under investigation include: Sodium fluoride / silica and carbopol, 0.5g (DRUG), Sodium fluoride / silica and carbopol, 1.5g (DRUG), Fluoride free dentifrice (OTHER).
Who is sponsoring clinical trial NCT01563172?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01563172's enrollment target sits among peer trials
65 1091st of 2000 higher than 903 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03366116 · 65 participants · Phase 1
5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors
- NCT03603730 · 65 participants · NA
Vagal Nerve Stimulation for Functional Dyspepsia and Gastroparesis
- NCT03796559 · 65 participants · NA
Magseed Enabled Long-Term Localization of Axillary Lymph Nodes
- NCT03993106 · 65 participants · Phase 2
A Study of sEphB4-HSA in Kaposi Sarcoma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI