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NCT01535235 · ClinicalTrials.gov registry record · Phase 4

ACE Inhibitors to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Patients: A Pilot Study

A Phase 4 study, sponsored by University of California, San Francisco.

Completed
Registry status
Phase 4
Development phase
31
Enrollment target

NCT01535235 is a Phase 4 study that has completed, run by University of California, San Francisco. The registered enrollment target is 31 participants.

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The verdict

NCT01535235, a Phase 4 study, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 4
Development phase
31 participants
Enrollment target

Study Summary

The investigators propose a proof-of-concept, pathogenesis-oriented, randomized, placebo-controlled pilot study to assess whether the addition of an angiotensin converting enzyme (ACE) inhibitor to standard Highly Active Antiretroviral Therapy (HAART) reverses lymphoid fibrosis, and whether this leads to more effective HIV-specific host immune responses and an accelerated clearance of the latent reservoir.

Interventions

  • DRUG Placebo
  • DRUG Lisinopril

Trial Details

FieldValue
Enrollment Target 31 participants
Start Date 2012-02
Est. Completion 2014-12
Phase Phase 4

What the Registry Record Tells You About NCT01535235

The ClinicalTrials.gov registry entry for NCT01535235 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01535235 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01535235 about?

NCT01535235 is a clinical study titled "ACE Inhibitors to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Patients: A Pilot Study". The investigators propose a proof-of-concept, pathogenesis-oriented, randomized, placebo-controlled pilot study to assess whether the addition of an angiotensin converting enzyme (ACE) inhibitor to standard Highly Active Antiretroviral Therapy (HAART) reverses lymphoid fibrosis, and whether this lea...

What is the current status of trial NCT01535235?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 31 participants. The study started on 2012-02. Estimated completion is 2014-12.

What interventions are being tested in trial NCT01535235?

The interventions under investigation include: Placebo (DRUG), Lisinopril (DRUG).

Who is sponsoring clinical trial NCT01535235?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.