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NCT01533636 · ClinicalTrials.gov registry record
CF And Effects of Drugs Mixed Ex Vivo With Sputum for Mucolytic Treatment
A clinical trial, sponsored by University of California, San Francisco.
- Completed
- Registry status
- 114
- Enrollment target
NCT01533636 is a clinical trial that has completed, run by University of California, San Francisco. The registered enrollment target is 114 participants.
The verdict
NCT01533636 has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- 114 participants
- Enrollment target
Study Summary
The investigators will collect samples of sputum from healthy volunteers and patients with cystic fibrosis for the purpose of: a) purifying airway mucins for plate-based binding studies and; b) assessment of the effects of carbohydrates on the rheologic properties of the sputum. This study has two hypotheses: 1. Lectins from Pseudomonas aeruginosa and Aspergillus fumigatus bind to airway mucins in a fucose-dependent manner, and this binding can be inhibited by fucosyl glycomimetic compounds. 2. Fucosyl glycomimetics will compete with Pseudomonas aeruginosa lectin (PA-IIL) and Aspergillus fumigatus lectin (AFL) and disrupt lectin-driven mucin cross-linking in CF sputum.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 114 participants |
| Start Date | 2012-07-17 |
| Est. Completion | 2026-02-04 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01533636
The ClinicalTrials.gov registry entry for NCT01533636 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 114 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01533636 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01533636 about?
NCT01533636 is a clinical study titled "CF And Effects of Drugs Mixed Ex Vivo With Sputum for Mucolytic Treatment". The investigators will collect samples of sputum from healthy volunteers and patients with cystic fibrosis for the purpose of: a) purifying airway mucins for plate-based binding studies and; b) assessment of the effects of carbohydrates on the rheologic properties of the sputum. This study has two ...
What is the current status of trial NCT01533636?
This trial is currently completed. The enrollment target is 114 participants. The study started on 2012-07-17. Estimated completion is 2026-02-04.
Who is sponsoring clinical trial NCT01533636?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
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