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NCT01523587 · ClinicalTrials.gov registry record · Phase 3

LUX-Lung 8: A Phase III Trial of Afatinib (BIBW 2992) Versus Erlotinib for the Treatment of Squamous Cell Lung Cancer After at Least One Prior Platinum Based Chemotherapy

A Phase 3 study, sponsored by Boehringer Ingelheim.

Completed
Registry status
Phase 3
Development phase
795
Enrollment target

NCT01523587 is a Phase 3 study that has completed, run by Boehringer Ingelheim. The registered enrollment target is 795 participants.

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The verdict

NCT01523587, a Phase 3 study, has completed, sponsored by Boehringer Ingelheim.

COMPLETED
Registry status
Phase 3
Development phase
795 participants
Enrollment target

Study Summary

This randomised, open-label phase III trial will be performed in patients with advanced squamous cell carcinoma of the lung requiring second-line treatment after receiving first-line platinum-based chemotherapy. The primary objective of this trial is to compare the efficacy of BIBW 2992 to erlotinib as second-line treatment in this group of patients.

Interventions

  • DRUG erlotinib
  • DRUG afatinib

Trial Details

FieldValue
Enrollment Target 795 participants
Start Date 2012-03-05
Est. Completion 2017-12-27
Phase Phase 3

Sponsor

Boehringer Ingelheim

515 total trials

What the Registry Record Tells You About NCT01523587

The ClinicalTrials.gov registry entry for NCT01523587 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 795 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Boehringer Ingelheim, which has 515 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which erlotinib is the first listed.

NCT01523587 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01523587 about?

NCT01523587 is a clinical study titled "LUX-Lung 8: A Phase III Trial of Afatinib (BIBW 2992) Versus Erlotinib for the Treatment of Squamous Cell Lung Cancer After at Least One Prior Platinum Based Chemotherapy". This randomised, open-label phase III trial will be performed in patients with advanced squamous cell carcinoma of the lung requiring second-line treatment after receiving first-line platinum-based chemotherapy. The primary objective of this trial is to compare the efficacy of BIBW 2992 to erlotinib...

What is the current status of trial NCT01523587?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 795 participants. The study started on 2012-03-05. Estimated completion is 2017-12-27.

What interventions are being tested in trial NCT01523587?

The interventions under investigation include: erlotinib (DRUG), afatinib (DRUG).

Who is sponsoring clinical trial NCT01523587?

This trial is sponsored by Boehringer Ingelheim, which has 515 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.