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NCT01507545 · ClinicalTrials.gov registry record · Phase 2
Morphotek Investigation in Colorectal Cancer: Research of MORAb-004 (MICRO)
A Phase 2 study, sponsored by Morphotek.
- Terminated
- Registry status
- Phase 2
- Development phase
- 154
- Enrollment target
NCT01507545: Clinical Trial Phase 2 study, sponsored by Morphotek.
NCT01507545 is a Phase 2 study that was terminated before completion, run by Morphotek. The registered enrollment target is 154 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (16% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01507545, a Phase 2 study, was terminated before completion, sponsored by Morphotek.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 154 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate whether therapy with MORAb-004 is effective and safe in the treatment of metastatic, colorectal cancer.
Primary Outcome
PFS based on Response Evaluation Criteria in Solid Tumors (RECIST) v.1.1 was defined as the time (in weeks) from the date of randomization to the date of the first observation of disease progression (PD) or death due to any cause. PD was defined as at least a 20 percent (%) increase in the sum of the longest diameter (LD) of target lesions, taking as reference the smallest sum LD recorded since the treatment started or the appearance of one or more new lesions. If progression or death was not ob
Interventions
- DRUG Placebo
- OTHER Best supportive care
- DRUG MORAb-004
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 154 participants |
| Start Date | 2012-03-27 |
| Est. Completion | 2013-10-20 |
| Phase | Phase 2 |
Why NCT01507545 stopped before completion
NCT01507545 is an interventional study that assigns participants to a tested intervention. The registered 154 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (16% higher).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT01507545 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01507545 about?
NCT01507545 is a clinical study titled "Morphotek Investigation in Colorectal Cancer: Research of MORAb-004 (MICRO)". The purpose of this study is to evaluate whether therapy with MORAb-004 is effective and safe in the treatment of metastatic, colorectal cancer.
What is the current status of trial NCT01507545?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 154 participants. The study started on 2012-03-27. Estimated completion is 2013-10-20.
What interventions are being tested in trial NCT01507545?
The interventions under investigation include: Placebo (DRUG), Best supportive care (OTHER), MORAb-004 (DRUG).
Who is sponsoring clinical trial NCT01507545?
This trial is sponsored by Morphotek, which has 20 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01507545's enrollment target sits among peer trials
154 448th of 2000 higher than 1,552 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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