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NCT01502787 · ClinicalTrials.gov registry record · Phase 4
Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients
A Phase 4 study, sponsored by University of Texas Southwestern Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 46
- Enrollment target
NCT01502787: Completed Phase 4 study, sponsored by University of Texas Southwestern Medical Center.
NCT01502787 is a Phase 4 study that has completed, run by University of Texas Southwestern Medical Center. The registered enrollment target is 46 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01502787, a Phase 4 study, has completed, sponsored by University of Texas Southwestern Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 46 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if Nebivolol a) attenuates the angiotensin II (Ang II)-induced increase in oxidative stress, thereby attenuating Ang II-induced vasoconstriction; and b) attenuates sympathetic mediated vasoconstriction during exercise, thereby reducing functional skeletal muscle ischemia in hypertensive patients.
Interventions
- DRUG Nebivolol
- DRUG Metoprolol succinate
- PROCEDURE Microneurography
- PROCEDURE Rhythmic handgrip exercise
- PROCEDURE Forearm blood flow
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 46 participants |
| Start Date | 2009-04 |
| Est. Completion | 2013-06 |
| Phase | Phase 4 |
What the finished NCT01502787 record still lists
NCT01502787 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 5 interventions - of which Nebivolol is the first listed.
NCT01502787 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01502787 about?
NCT01502787 is a clinical study titled "Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients". The purpose of this study is to determine if Nebivolol a) attenuates the angiotensin II (Ang II)-induced increase in oxidative stress, thereby attenuating Ang II-induced vasoconstriction; and b) attenuates sympathetic mediated vasoconstriction during exercise, thereby reducing functional skeletal mu...
What is the current status of trial NCT01502787?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 46 participants. The study started on 2009-04. Estimated completion is 2013-06.
What interventions are being tested in trial NCT01502787?
The interventions under investigation include: Nebivolol (DRUG), Metoprolol succinate (DRUG), Microneurography (PROCEDURE), Rhythmic handgrip exercise (PROCEDURE), Forearm blood flow (PROCEDURE).
Who is sponsoring clinical trial NCT01502787?
This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01502787's enrollment target sits among peer trials
46 1348th of 2000 higher than 647 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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