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NCT01475734 · ClinicalTrials.gov registry record · Phase 2

Albiglutide Glucose Clamp Study in Subjects With Type 2 Diabetes

A Phase 2 study of Diabetes Mellitus, Type 2, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 2
Development phase
44
Enrollment target
1
Study location

NCT01475734 is a Phase 2 study of Diabetes Mellitus, Type 2 that has completed, run by GlaxoSmithKline. The registered enrollment target is 44 participants, below the 4,485-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01475734, a Phase 2 study of Diabetes Mellitus, Type 2, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 2
Development phase
44 participants
Enrollment target
1
Study location

Study Summary

This is a stepped glucose clamp study designed to investigate the effect of treatment with albiglutide on counter-regulatory hormone responses and recovery from hypoglycemia in subjects with Type 2 diabetes mellitus. A single dose of albiglutide or placebo will be given prior to a stepped hyper- and hypoglycemic clamp. The goal of this study is to demonstrate that albiglutide increases insulin secretion and decreases glucagon levels in a glucose-dependent manner.

Conditions Studied

Interventions

  • BIOLOGICAL placebo
  • BIOLOGICAL albiglutide

Study Locations (1)

California

  • GSK Investigational Site - Chula Vista

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2011-12
Est. Completion 2012-07
Phase Phase 2

Sponsor

GlaxoSmithKline

1,345 total trials

What the Registry Record Tells You About NCT01475734

The ClinicalTrials.gov registry entry for NCT01475734 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,485-participant average among 348 other Diabetes Mellitus, Type 2 trials with a reported enrollment target (99% lower). The listed sponsor is GlaxoSmithKline, which has 1,345 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Diabetes Mellitus, Type 2 appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.

NCT01475734 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT01475734 about?

NCT01475734 is a clinical study titled "Albiglutide Glucose Clamp Study in Subjects With Type 2 Diabetes". This is a stepped glucose clamp study designed to investigate the effect of treatment with albiglutide on counter-regulatory hormone responses and recovery from hypoglycemia in subjects with Type 2 diabetes mellitus. A single dose of albiglutide or placebo will be given prior to a stepped hyper- and...

What is the current status of trial NCT01475734?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2011-12. Estimated completion is 2012-07.

What conditions does trial NCT01475734 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 2.

What interventions are being tested in trial NCT01475734?

The interventions under investigation include: placebo (BIOLOGICAL), albiglutide (BIOLOGICAL).

Who is sponsoring clinical trial NCT01475734?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01475734 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.