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NCT01441154 · ClinicalTrials.gov registry record
Metabolic Effects of Synthetic Thyroid Hormone for Thyroid Cancer Treatment
A clinical trial, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- Completed
- Registry status
- 16
- Enrollment target
NCT01441154 is a clinical trial that has completed, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 16 participants.
The verdict
NCT01441154 has completed, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- COMPLETED
- Registry status
- 16 participants
- Enrollment target
Study Summary
Background: \- Thyroid hormone is produced by the thyroid gland, an organ at the base of the neck. Thyroid hormone controls the body's metabolism and the function of many organs. The thyroid gland produces two forms of thyroid hormone: T4 and T3. People who have thyroid cancer are treated with thyroid hormone therapy (synthetic T4, levothyroxine), which at times needs to be stopped to allow for cancer treatments. At these times, a different form of thyroid hormone (synthetic T3, liothyronine) is used to reduce the symptoms caused by low levels of thyroid hormone. Researchers want to know more about how changes in T3 hormone affect the body and organ function. Objectives: \- To study how changes in T3 hormone levels affect the body and organ function. Eligibility: \- Individuals at least 18 years of age who have had most or all of their thyroid removed to treat thyroid cancer who need to stop taking their regular thyroid hormone dose in preparation for the treatment of thyroid cancer. Design: * The study involves a screening visit and a baseline evaluation. It also includes an 11-day inpatient hospital stay. * Participants will be screened with a physical exam and medical history. They will also have blood tests and a neck ultrasound. * Participants will be evaluated with a physical exam, blood tests, and the following procedures: * Glucose tolerance test to measure blood sugar * Tests of body fat, muscle strength, and calorie burning levels * Imaging studies of the heart, liver, and thigh muscles * Quality of life questionnaires * Food preference and diet questionnaires * After 4 weeks of treatment with T3 hormone, participants will have an 11-day inpatient hospital stay to study the effect of thyroid hormone on their metabolism. The stay will involve the same tests done in the baseline evaluation.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2011-09-20 |
| Est. Completion | 2013-12-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01441154
The ClinicalTrials.gov registry entry for NCT01441154 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01441154 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01441154 about?
NCT01441154 is a clinical study titled "Metabolic Effects of Synthetic Thyroid Hormone for Thyroid Cancer Treatment". Background: \- Thyroid hormone is produced by the thyroid gland, an organ at the base of the neck. Thyroid hormone controls the body's metabolism and the function of many organs. The thyroid gland produces two forms of thyroid hormone: T4 and T3. People who have thyroid cancer are treated with thyr...
What is the current status of trial NCT01441154?
This trial is currently completed. The enrollment target is 16 participants. The study started on 2011-09-20. Estimated completion is 2013-12-12.
Who is sponsoring clinical trial NCT01441154?
This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.
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