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NCT01386346 · ClinicalTrials.gov registry record · Phase 1

Epigenetic Priming Using Azacitidine With Neoadjuvant Chemotherapy for Resectable Esophageal Cancer

A Phase 1 study of Esophageal Cancer and Malignant Neoplasm of Cardio-esophageal Junction of Stomach, sponsored by Weill Medical College of Cornell University.

Completed
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT01386346 is a Phase 1 study of Esophageal Cancer and Malignant Neoplasm of Cardio-esophageal Junction of Stomach that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 12 participants, below the 499-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01386346, a Phase 1 study of Esophageal Cancer and Malignant Neoplasm of Cardio-esophageal Junction of Stomach, has completed, sponsored by Weill Medical College of Cornell University.

COMPLETED
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to see whether giving azacitidine before each cycle of chemotherapy prior to surgery is safe.

Interventions

  • DRUG Capecitabine
  • DRUG Oxaliplatin
  • DRUG Azacitidine
  • DRUG Epirubicin

Study Locations (1)

New York

  • Weill Cornell Medical College - New York

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2011-06
Est. Completion 2018-09
Phase Phase 1

What the Registry Record Tells You About NCT01386346

The ClinicalTrials.gov registry entry for NCT01386346 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 12 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 499-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (98% lower). The listed sponsor is Weill Medical College of Cornell University, which has 701 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Esophageal Cancer appearing as the primary indexed condition, and to 4 interventions - of which Capecitabine is the first listed.

NCT01386346 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT01386346 about?

NCT01386346 is a clinical study titled "Epigenetic Priming Using Azacitidine With Neoadjuvant Chemotherapy for Resectable Esophageal Cancer". The purpose of this study is to see whether giving azacitidine before each cycle of chemotherapy prior to surgery is safe.

What is the current status of trial NCT01386346?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2011-06. Estimated completion is 2018-09.

What conditions does trial NCT01386346 study?

This clinical trial studies the following conditions: Esophageal Cancer, Malignant Neoplasm of Cardio-esophageal Junction of Stomach.

What interventions are being tested in trial NCT01386346?

The interventions under investigation include: Capecitabine (DRUG), Oxaliplatin (DRUG), Azacitidine (DRUG), Epirubicin (DRUG).

Who is sponsoring clinical trial NCT01386346?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01386346 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.