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NCT01369914 · ClinicalTrials.gov registry record
The Natural History of Graft-Versus-Host Disease in the Eyes
A clinical trial, sponsored by National Eye Institute (NEI).
- Completed
- Registry status
- 61
- Enrollment target
NCT01369914 is a clinical trial that has completed, run by National Eye Institute (NEI). The registered enrollment target is 61 participants.
The verdict
NCT01369914 has completed, sponsored by National Eye Institute (NEI).
- COMPLETED
- Registry status
- 61 participants
- Enrollment target
Study Summary
Background: * Stem cell transplantation (SCT) is used to treat some kinds of cancer, blood cell disorders, and immune disorders. Stem cells from a donor s blood are used to replace the recipient s stem cells in the bone marrow. The recipient s bone marrow can then produce new blood cells. Some of these new cells involved in the immune system are like the donor s cells. Sometimes immune cells from the SCT attack the recipient s normal tissues, including the eyes. This type of immune attack is called graft-versus-host disease, or GVHD. * The symptoms of ocular GVHD include eye pain, irritation, dryness, and inflammation. When it is severe and if it does not respond well to treatment, ocular GVHD may also cause vision loss. Objective: \- To learn more about graft-versus-host disease (GVHD) of the eyes in people who have had stem cell transplantation. Eligibility: * Participants must be at least 18 years of age. * They must be taking part in a study at the National Cancer Institute (NCI) or the National Heart, Lung and Blood Institute (NHLBI). * They must have a SCT scheduled within the next 30 days. Design: * The study lasts for 1 year and includes six visits to the National Eye Institute. (There is an optional visit about 1 month before your SCT.) When possible, visits for this study will be scheduled so that they can be done on the same day as your visits for the NCI or NHLBI protocol that you are taking part in. * At each visit, participants will have a medical exam and an eye history will be taken. They will have an eye exam and a test to measure the ability to make tears. Those in the study will also have tear fluid collected for analysis in a lab. Tear fluid collection is a painless process. Blood will be drawn during certain visits if it has not already been collected by the transplant team.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2011-05-20 |
| Est. Completion | 2016-02-05 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01369914
The ClinicalTrials.gov registry entry for NCT01369914 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 61 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Eye Institute (NEI), which has 221 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01369914 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01369914 about?
NCT01369914 is a clinical study titled "The Natural History of Graft-Versus-Host Disease in the Eyes". Background: * Stem cell transplantation (SCT) is used to treat some kinds of cancer, blood cell disorders, and immune disorders. Stem cells from a donor s blood are used to replace the recipient s stem cells in the bone marrow. The recipient s bone marrow can then produce new blood cells. Some of t...
What is the current status of trial NCT01369914?
This trial is currently completed. The enrollment target is 61 participants. The study started on 2011-05-20. Estimated completion is 2016-02-05.
Who is sponsoring clinical trial NCT01369914?
This trial is sponsored by National Eye Institute (NEI), which has 221 total clinical trials registered on ClinicalTrials.gov.
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