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NCT01353196 · ClinicalTrials.gov registry record
Asymptomatic Carotid Stenosis: Cognitive Function and Plaque Correlates
A clinical trial, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- 170
- Enrollment target
NCT01353196: Completed study, sponsored by VA Office of Research and Development.
NCT01353196 is a clinical trial that has completed, run by VA Office of Research and Development. The registered enrollment target is 170 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01353196 has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- 170 participants
- Enrollment target
Study Summary
Carotid artery plaques are known to cause stroke. Cognitive impairment is an insidious but poorly understood problem in patients with carotid plaques. Cognitive function describes how people perform mental processes such as thinking, learning and problem solving. Asymptomatic carotid plaques may affect 1 million Veterans who may be at risk for cognitive impairment. In this study, the investigators will uncover the extent of cognitive impairment in Veterans with carotid stenosis who are currently labeled "asymptomatic". Programs to prevent or mitigate cognitive impairment will depend on identifying the mechanisms by which this occurs. The investigators will use sophisticated 3D imaging techniques developed by the group to measure the structure and composition of plaques, number of particles breaking off from them, blood levels of chemicals that could disrupt them, and blood flow restriction to the brain from them. This will help identify patients at risk for cognitive impairment who may benefit from preventative measures and improve selection of patients to decrease unnecessary surgical procedures.
Primary Outcome
composite of multiple cognitive function test scores scores are reported as mean +/- standard deviation 0 = worst 100 = best
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 170 participants |
| Start Date | 2011-05-15 |
| Est. Completion | 2018-02-28 |
What the finished NCT01353196 record still lists
NCT01353196 is an observational study that tracks outcomes without assigning an intervention. The registered 170 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01353196 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01353196 about?
NCT01353196 is a clinical study titled "Asymptomatic Carotid Stenosis: Cognitive Function and Plaque Correlates". Carotid artery plaques are known to cause stroke. Cognitive impairment is an insidious but poorly understood problem in patients with carotid plaques. Cognitive function describes how people perform mental processes such as thinking, learning and problem solving. Asymptomatic carotid plaques may aff...
What is the current status of trial NCT01353196?
This trial is currently completed. The enrollment target is 170 participants. The study started on 2011-05-15. Estimated completion is 2018-02-28.
Who is sponsoring clinical trial NCT01353196?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
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