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NCT01323621 · ClinicalTrials.gov registry record · Phase 3

Study Evaluating the 24-Hour Pulmonary Function Profile of Fluticasone Furoate (FF) /GW642444 (Vilanterol) (VI) Inhalation Powder 100/25mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

A Phase 3 study of Pulmonary Disease, Chronic Obstructive, sponsored by GlaxoSmithKline.

Completed
Registry status
Phase 3
Development phase
512
Enrollment target
20
Study locations

NCT01323621 is a Phase 3 study of Pulmonary Disease, Chronic Obstructive that has completed, run by GlaxoSmithKline. The registered enrollment target is 512 participants, below the 1,037-participant average among 74 other Pulmonary Disease, Chronic Obstructive trials with a reported enrollment target (51% lower). The trial reports 20 study locations across 15 states.

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The verdict

NCT01323621, a Phase 3 study of Pulmonary Disease, Chronic Obstructive, has completed, sponsored by GlaxoSmithKline.

COMPLETED
Registry status
Phase 3
Development phase
512 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to evaluate the 24-hour spirometry effect (FEV1) of FF/VI 100/25mcg once daily compared with Fluticasone Propionate/Salmeterol 250/50mcg twice daily over a 12-week treatment period in subjects with COPD.

Interventions

  • DRUG Fluticasone Furoate 100mcg/ GW642444 (vilanterol) 25mcg
  • DRUG Fluticasone Propionate 250mcg / salmeterol 50mcg
  • DRUG Double-dummy placebo
  • DRUG Salbutamol as needed

Study Locations (20)

South Carolina

  • GSK Investigational Site - Gaffney
  • GSK Investigational Site - Orangeburg
  • GSK Investigational Site - Seneca
  • GSK Investigational Site - Spartanburg

Campania

  • GSK Investigational Site - Naples
  • GSK Investigational Site - San Felice A Cancello Caserta
  • GSK Investigational Site - Telese Terme (BN)

Alabama

  • GSK Investigational Site - Jasper

California

  • GSK Investigational Site - Riverside

Florida

  • GSK Investigational Site - DeLand

Idaho

  • GSK Investigational Site - Coeur d'Alene

Minnesota

  • GSK Investigational Site - Minneapolis

Ohio

  • GSK Investigational Site - Cincinnati

Trial Details

FieldValue
Enrollment Target 512 participants
Start Date 2011-03-18
Est. Completion 2012-01-24
Phase Phase 3

Sponsor

GlaxoSmithKline

1,345 total trials

What the Registry Record Tells You About NCT01323621

The ClinicalTrials.gov registry entry for NCT01323621 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 512 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,037-participant average among 74 other Pulmonary Disease, Chronic Obstructive trials with a reported enrollment target (51% lower). The listed sponsor is GlaxoSmithKline, which has 1,345 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pulmonary Disease, Chronic Obstructive appearing as the primary indexed condition, and to 4 interventions - of which Fluticasone Furoate 100mcg/ GW642444 (vilanterol) 25mcg is the first listed.

NCT01323621 reports 20 study locations spanning 15 distinct geographic areas - top geographies include South Carolina, Campania, Alabama.

Frequently Asked Questions

What is clinical trial NCT01323621 about?

NCT01323621 is a clinical study titled "Study Evaluating the 24-Hour Pulmonary Function Profile of Fluticasone Furoate (FF) /GW642444 (Vilanterol) (VI) Inhalation Powder 100/25mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)". The purpose of this study is to evaluate the 24-hour spirometry effect (FEV1) of FF/VI 100/25mcg once daily compared with Fluticasone Propionate/Salmeterol 250/50mcg twice daily over a 12-week treatment period in subjects with COPD.

What is the current status of trial NCT01323621?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 512 participants. The study started on 2011-03-18. Estimated completion is 2012-01-24.

What conditions does trial NCT01323621 study?

This clinical trial studies the following conditions: Pulmonary Disease, Chronic Obstructive.

What interventions are being tested in trial NCT01323621?

The interventions under investigation include: Fluticasone Furoate 100mcg/ GW642444 (vilanterol) 25mcg (DRUG), Fluticasone Propionate 250mcg / salmeterol 50mcg (DRUG), Double-dummy placebo (DRUG), Salbutamol as needed (DRUG).

Who is sponsoring clinical trial NCT01323621?

This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01323621 being conducted?

This trial has 20 study locations across Alabama, California, Florida, Idaho, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.