Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01322009 · ClinicalTrials.gov registry record · Phase 1

Overcoming Membrane Transporters to Improve CNS Drug Delivery - Improving Brain Antioxidants After Traumatic Brain Injury

A Phase 1 study, sponsored by University of Pittsburgh.

Completed
Registry status
Phase 1
Development phase
14
Enrollment target

NCT01322009 is a Phase 1 study that has completed, run by University of Pittsburgh. The registered enrollment target is 14 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01322009, a Phase 1 study, has completed, sponsored by University of Pittsburgh.

COMPLETED
Registry status
Phase 1
Development phase
14 participants
Enrollment target

Study Summary

The overall purpose of this research study is to investigate the safety of pharmacological therapies that may potentially improve pediatric outcomes after traumatic brain injury. Traumatic brain injuries are the leading cause of death and disability among children and young adults. Hypothesis: Combinational therapy with a membrane transporter and antioxidant are safe after TBI and can overcome barriers to the brain and synergistically improve bioavailability and efficacy the antioxidant content of the body and CNS after TBI.

Interventions

  • DRUG Placebo
  • DRUG Probenecid and N-acetyl cysteine

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2011-03
Est. Completion 2015-03
Phase Phase 1

Sponsor

University of Pittsburgh

1,238 total trials

What the Registry Record Tells You About NCT01322009

The ClinicalTrials.gov registry entry for NCT01322009 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01322009 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01322009 about?

NCT01322009 is a clinical study titled "Overcoming Membrane Transporters to Improve CNS Drug Delivery - Improving Brain Antioxidants After Traumatic Brain Injury". The overall purpose of this research study is to investigate the safety of pharmacological therapies that may potentially improve pediatric outcomes after traumatic brain injury. Traumatic brain injuries are the leading cause of death and disability among children and young adults. Hypothesis: Comb...

What is the current status of trial NCT01322009?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2011-03. Estimated completion is 2015-03.

What interventions are being tested in trial NCT01322009?

The interventions under investigation include: Placebo (DRUG), Probenecid and N-acetyl cysteine (DRUG).

Who is sponsoring clinical trial NCT01322009?

This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.