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NCT01307956 · ClinicalTrials.gov registry record · Phase 2

Panitumumab, Combination Chemotherapy, & Radiation Therapy in Esophageal or Gastroesophageal Junction Cancer

A Phase 2 study, sponsored by University of Nebraska.

Terminated
Registry status
Phase 2
Development phase
11
Enrollment target

NCT01307956 is a Phase 2 study that was terminated before completion, run by University of Nebraska. The registered enrollment target is 11 participants.

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The verdict

NCT01307956, a Phase 2 study, was terminated before completion, sponsored by University of Nebraska.

TERMINATED
Registry status
Phase 2
Development phase
11 participants
Enrollment target

Study Summary

This phase II trial is studying how well giving panitumumab, combination chemotherapy, and radiation therapy together before surgery works in treating patients with advanced esophageal or gastroesophageal (GE) junction cancer. Monoclonal antibodies, such as panitumumab, may interfere with the ability of tumor cells to grow and spread. Drugs used in chemotherapy, such as oxaliplatin, leucovorin calcium, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays to kill tumor cells. Giving monoclonal antibody therapy together with chemotherapy and radiation therapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed.

Interventions

  • DRUG Fluorouracil
  • DRUG Oxaliplatin
  • OTHER Laboratory Biomarker Analysis
  • BIOLOGICAL Panitumumab
  • DRUG Leucovorin Calcium

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2011-02-28
Est. Completion 2015-12-23
Phase Phase 2

Sponsor

University of Nebraska

407 total trials

What the Registry Record Tells You About NCT01307956

The ClinicalTrials.gov registry entry for NCT01307956 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Nebraska, which has 407 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Fluorouracil is the first listed.

NCT01307956 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01307956 about?

NCT01307956 is a clinical study titled "Panitumumab, Combination Chemotherapy, & Radiation Therapy in Esophageal or Gastroesophageal Junction Cancer". This phase II trial is studying how well giving panitumumab, combination chemotherapy, and radiation therapy together before surgery works in treating patients with advanced esophageal or gastroesophageal (GE) junction cancer. Monoclonal antibodies, such as panitumumab, may interfere with the abilit...

What is the current status of trial NCT01307956?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 11 participants. The study started on 2011-02-28. Estimated completion is 2015-12-23.

What interventions are being tested in trial NCT01307956?

The interventions under investigation include: Fluorouracil (DRUG), Oxaliplatin (DRUG), Laboratory Biomarker Analysis (OTHER), Panitumumab (BIOLOGICAL), Leucovorin Calcium (DRUG).

Who is sponsoring clinical trial NCT01307956?

This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.