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NCT01299038 · ClinicalTrials.gov registry record · Phase 2

Rosuvastatin to Lower Circulating Tissue Factor Bearing Microparticles in Metastatic Breast Cancer

A Phase 2 study of Breast Cancer, sponsored by Beth Israel Deaconess Medical Center.

Completed
Registry status
Phase 2
Development phase
20
Enrollment target
2
Study locations

NCT01299038: Completed Phase 2 study of Breast Cancer, sponsored by Beth Israel Deaconess Medical Center.

NCT01299038 is a Phase 2 study of Breast Cancer that has completed, run by Beth Israel Deaconess Medical Center. The registered enrollment target is 20 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01299038, a Phase 2 study of Breast Cancer, has completed, sponsored by Beth Israel Deaconess Medical Center.

COMPLETED
Registry status
Phase 2
Development phase
20 participants
Enrollment target
2
Study locations

Study Summary

Research studies have shown a strong association between cancer and blood clots in the veins (also known as deep vein thrombosis). These blood clots can flow to the lungs (pulmonary embolism) which in severe cases may be life threatening. Studies have demonstrated that increases in microparticles may contribute to the development of deep vein thrombosis in cancer patients. The purpose of this research study is to see if rosuvastatin lowers the number of tissue factor bearing microparticles in the blood (TFMP). TFMP are small particles that are generated from different types of blood cells in the body. In people who have cancer, TFMP are thought to be generated from cancer cells and may represent a risk factor for deep vein thrombosis.

Primary Outcome

Comparison of plasma microparticle concentration between baseline and week 4

Conditions Studied

Interventions

  • DRUG rosuvastatin

Study Locations (2)

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston
  • Dana-Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2010-10
Est. Completion 2013-12
Phase Phase 2

What the finished NCT01299038 record still lists

NCT01299038 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which rosuvastatin is the first listed.

NCT01299038 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT01299038 about?

NCT01299038 is a clinical study titled "Rosuvastatin to Lower Circulating Tissue Factor Bearing Microparticles in Metastatic Breast Cancer". Research studies have shown a strong association between cancer and blood clots in the veins (also known as deep vein thrombosis). These blood clots can flow to the lungs (pulmonary embolism) which in severe cases may be life threatening. Studies have demonstrated that increases in microparticles ma...

What is the current status of trial NCT01299038?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2010-10. Estimated completion is 2013-12.

What conditions does trial NCT01299038 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT01299038?

The interventions under investigation include: rosuvastatin (DRUG).

Who is sponsoring clinical trial NCT01299038?

This trial is sponsored by Beth Israel Deaconess Medical Center, which has 488 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01299038 being conducted?

This trial has 2 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01299038's enrollment target sits among peer trials

20 1079th of 1224 higher than 112 of 1,224 other Breast Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01299038, the US trial registry maintained by the National Library of Medicine. NCT01299038 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.