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NCT01281852 · ClinicalTrials.gov registry record · Phase 1

Paclitaxel, Cisplatin, and Veliparib in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer

A Phase 1 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
37
Enrollment target

NCT01281852: Completed Phase 1 study, sponsored by National Cancer Institute (NCI).

NCT01281852 is a Phase 1 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 37 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01281852, a Phase 1 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
37 participants
Enrollment target

Study Summary

This phase I clinical trial studies the side effects and best dose of veliparib when given together with paclitaxel and cisplatin and to see how well they work in treating patients with cervical cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment or that has come back. Drugs used in chemotherapy, such as paclitaxel and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Veliparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving more than one drug (combination chemotherapy) and giving chemotherapy together with veliparib may kill more tumor cells.

Interventions

  • DRUG Cisplatin
  • OTHER Laboratory Biomarker Analysis
  • DRUG Paclitaxel
  • DRUG Veliparib

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2011-03-14
Est. Completion 2017-02-11
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT01281852

The ClinicalTrials.gov registry entry for NCT01281852 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Cisplatin is the first listed.

NCT01281852 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01281852 about?

NCT01281852 is a clinical study titled "Paclitaxel, Cisplatin, and Veliparib in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer". This phase I clinical trial studies the side effects and best dose of veliparib when given together with paclitaxel and cisplatin and to see how well they work in treating patients with cervical cancer that has spread to other places in the body and usually cannot be cured or controlled with treatme...

What is the current status of trial NCT01281852?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 37 participants. The study started on 2011-03-14. Estimated completion is 2017-02-11.

What interventions are being tested in trial NCT01281852?

The interventions under investigation include: Cisplatin (DRUG), Laboratory Biomarker Analysis (OTHER), Paclitaxel (DRUG), Veliparib (DRUG).

Who is sponsoring clinical trial NCT01281852?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.