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COMPLETED Phase 3

Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes

NCT01272219 · View on ClinicalTrials.gov ↗

Study Summary

This trial is conducted in Africa, Asia, Europe, Oceania, North America and South America. The aim of this clinical trial is to evaluate the potential of liraglutide to induce and maintain weight loss over 56 weeks in obese subjects or overweight subjects with co-morbidities. Furthermore, the aim is to investigate the long term potential of liraglutide to delay the onset of type 2 diabetes in subjects diagnosed with pre-diabetes at baseline. Based on body mass index (BMI) and pre-diabetes status, subjects will be randomised to either 68 weeks (56 weeks of randomised treatment followed by a 12 week re-randomised treatment period) or 160 weeks of treatment (160 week treatment will only be applicable to subjects with pre-diabetes status at baseline).

Interventions

  • DRUG placebo
  • DRUG liraglutide

Study Locations (20)

California

  • Novo Nordisk Investigational Site — Anaheim
  • Novo Nordisk Investigational Site — Concord
  • Novo Nordisk Investigational Site — Huntington Beach
  • Novo Nordisk Investigational Site — La Jolla
  • Novo Nordisk Investigational Site — San Diego
  • Novo Nordisk Investigational Site — San Diego
  • Novo Nordisk Investigational Site — Santa Monica

Florida

  • Novo Nordisk Investigational Site — Boynton Beach
  • Novo Nordisk Investigational Site — Bradenton
  • Novo Nordisk Investigational Site — Crystal River
  • Novo Nordisk Investigational Site — Daytona Beach
  • Novo Nordisk Investigational Site — Jacksonville

Colorado

  • Novo Nordisk Investigational Site — Aurora
  • Novo Nordisk Investigational Site — Colorado Springs
  • Novo Nordisk Investigational Site — Golden

Connecticut

  • Novo Nordisk Investigational Site — New London
  • Novo Nordisk Investigational Site — Waterbury

Alabama

  • Novo Nordisk Investigational Site — Birmingham

Arizona

  • Novo Nordisk Investigational Site — Phoenix

District of Columbia

  • Novo Nordisk Investigational Site — Washington D.C.

Trial Details

FieldValue
Enrollment Target 3,731 participants
Start Date 2011-06-01
Est. Completion 2015-03-02
Phase Phase 3

Sponsor

Novo Nordisk A/S

189 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT01272219

The ClinicalTrials.gov registry entry for NCT01272219 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 3,731 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novo Nordisk A/S, which has 189 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions — of which placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT01272219 reports 20 study locations spanning 7 distinct geographic areas — top geographies include California, Florida, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT01272219 about?

NCT01272219 is a clinical study titled "Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes". This trial is conducted in Africa, Asia, Europe, Oceania, North America and South America. The aim of this clinical trial is to evaluate the potential of liraglutide to induce and maintain weight loss over 56 weeks in obese subjects or overweight subjects with co-morbidities. Furthermore, the aim i...

What is the current status of trial NCT01272219?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 3,731 participants. The study started on 2011-06-01. Estimated completion is 2015-03-02.

What conditions does trial NCT01272219 study?

This clinical trial studies the following conditions: Obesity, Metabolism and Nutrition Disorder. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT01272219?

The interventions under investigation include: placebo (DRUG), liraglutide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT01272219?

This trial is sponsored by Novo Nordisk A/S, which has 189 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT01272219 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial