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NCT01266057 · ClinicalTrials.gov registry record · Phase 1

Sirolimus or Vorinostat and Hydroxychloroquine in Advanced Cancer

A Phase 1 study of Advanced Cancers, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 1
Development phase
143
Enrollment target
1
Study location

NCT01266057 is a Phase 1 study of Advanced Cancers that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 143 participants, above the 56-participant average among 10 other Advanced Cancers trials with a reported enrollment target (155% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT01266057, a Phase 1 study of Advanced Cancers, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
143 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical research study is to find the highest tolerable dose of sirolimus or vorinostat that can be given in combination with hydroxychloroquine to patients with advanced cancer. The safety of these drug combinations will also be studied.

Conditions Studied

Advanced Cancers

Interventions

  • DRUG Sirolimus
  • DRUG Vorinostat
  • DRUG Hydroxychloroquine

Study Locations (1)

Texas

  • University of Texas MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 143 participants
Start Date 2011-04-28
Est. Completion 2021-02-11
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

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What the Registry Record Tells You About NCT01266057

The ClinicalTrials.gov registry entry for NCT01266057 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 143 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 56-participant average among 10 other Advanced Cancers trials with a reported enrollment target (155% higher). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Cancers appearing as the primary indexed condition, and to 3 interventions - of which Sirolimus is the first listed.

NCT01266057 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT01266057 about?

NCT01266057 is a clinical study titled "Sirolimus or Vorinostat and Hydroxychloroquine in Advanced Cancer". The goal of this clinical research study is to find the highest tolerable dose of sirolimus or vorinostat that can be given in combination with hydroxychloroquine to patients with advanced cancer. The safety of these drug combinations will also be studied.

What is the current status of trial NCT01266057?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 143 participants. The study started on 2011-04-28. Estimated completion is 2021-02-11.

What conditions does trial NCT01266057 study?

This clinical trial studies the following conditions: Advanced Cancers.

What interventions are being tested in trial NCT01266057?

The interventions under investigation include: Sirolimus (DRUG), Vorinostat (DRUG), Hydroxychloroquine (DRUG).

Who is sponsoring clinical trial NCT01266057?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01266057 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.