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NCT01262625 · ClinicalTrials.gov registry record · NA
Randomized Evaluation of Patients With Stable Angina Comparing Diagnostic Examinations
A NA study, sponsored by American College of Radiology.
- Terminated
- Registry status
- NA
- Development phase
- 1,050
- Enrollment target
NCT01262625: Clinical Trial NA study, sponsored by American College of Radiology.
NCT01262625 is a NA study that was terminated before completion, run by American College of Radiology. The registered enrollment target is 1,050 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01262625, a NA study, was terminated before completion, sponsored by American College of Radiology.
- TERMINATED
- Registry status
- NA
- Development phase
- 1,050 participants
- Enrollment target
Study Summary
This randomized, controlled, diagnostic, multicenter trial will compare two diagnostic imaging pathways--coronary computed tomography angiography (CCTA) and single photon emission tomography (SPECT) myocardial perfusion imaging (MPI)--to determine the incidence of major adverse coronary events (MACE), defined as myocardial infarction (MI) or cardiac-related death, and cross-over to revascularization. CCTA may be used to direct patients with symptoms of stable angina or angina equivalent to optimal medical therapy (OMT). The use of CCTA as a diagnostic tool for angina symptoms will be associated with no increase in MACE or revascularization, decreased cost, reduced risks (e.g., less radiation exposure), additional insights into alternate explanations of chest pain, and increased cost-effectiveness in comparison with use of SPECT MPI/invasive coronary angiography (ICA).
Primary Outcome
To compare outcomes of participants with symptoms of stable angina or angina equivalent evaluated with an anatomic imaging strategy using CCTA as initial method of computer-aided diagnosis (CAD) (Group A) to a combined functional and anatomic imaging strategy of SPECT MPI/ICA (Group B) as a guide to Optimal Medical Therapy (OMT) alone. The analysis was conducted from an intent-to-treat perspective
Interventions
- DEVICE CCTA
- DEVICE SPECT MPI/ICA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,050 participants |
| Start Date | 2011-05-20 |
| Est. Completion | 2015-02 |
| Phase | NA |
Why NCT01262625 stopped before completion
NCT01262625 is an interventional study that assigns participants to a tested intervention. Its 1,050 participants enrollment target places it among the larger protocols in the corpus, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 2 interventions - of which CCTA is the first listed.
NCT01262625 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01262625 about?
NCT01262625 is a clinical study titled "Randomized Evaluation of Patients With Stable Angina Comparing Diagnostic Examinations". This randomized, controlled, diagnostic, multicenter trial will compare two diagnostic imaging pathways--coronary computed tomography angiography (CCTA) and single photon emission tomography (SPECT) myocardial perfusion imaging (MPI)--to determine the incidence of major adverse coronary events (MACE...
What is the current status of trial NCT01262625?
This trial is currently terminated. It is a NA study. The enrollment target is 1,050 participants. The study started on 2011-05-20. Estimated completion is 2015-02.
What interventions are being tested in trial NCT01262625?
The interventions under investigation include: CCTA (DEVICE), SPECT MPI/ICA (DEVICE).
Who is sponsoring clinical trial NCT01262625?
This trial is sponsored by American College of Radiology, which has 14 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01262625's enrollment target sits among peer trials
1,050 99th of 2000 higher than 1,901 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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