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NCT01256268 · ClinicalTrials.gov registry record · Phase 1
Carboplatin/Taxol/Ridaforolimus in Endometrial, Ovarian and Solids
A Phase 1 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT01256268: Completed Phase 1 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
NCT01256268 is a Phase 1 study that has completed, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01256268, a Phase 1 study, has completed, sponsored by H. Lee Moffitt Cancer Center and Research Institute.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
The purpose of this study is to: * Test the safety of a new investigational drug called MK-8669 (ridaforolimus) * Determine the maximum tolerated dose of MK-8669 * Determine the effectiveness of the maximum tolerated dose of MK-8669
Primary Outcome
To determine the maximal tolerated dose of oral ridaforolimus in combination with paclitaxel and carboplatin during the first cycle of treatment.
Interventions
- DRUG Paclitaxel
- DRUG carboplatin
- DRUG Ridaforolimus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2011-06-13 |
| Est. Completion | 2017-08-03 |
| Phase | Phase 1 |
What the finished NCT01256268 record still lists
NCT01256268 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 3 interventions - of which Paclitaxel is the first listed.
NCT01256268 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01256268 about?
NCT01256268 is a clinical study titled "Carboplatin/Taxol/Ridaforolimus in Endometrial, Ovarian and Solids". The purpose of this study is to: * Test the safety of a new investigational drug called MK-8669 (ridaforolimus) * Determine the maximum tolerated dose of MK-8669 * Determine the effectiveness of the maximum tolerated dose of MK-8669
What is the current status of trial NCT01256268?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2011-06-13. Estimated completion is 2017-08-03.
What interventions are being tested in trial NCT01256268?
The interventions under investigation include: Paclitaxel (DRUG), carboplatin (DRUG), Ridaforolimus (DRUG).
Who is sponsoring clinical trial NCT01256268?
This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01256268's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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