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NCT01247220 · ClinicalTrials.gov registry record · Phase 2
REtinal Vein OccLUsion Treatment With Scatter Laser Guided by UWFA in combiNAtion With Ranibizumab Study
A Phase 2 study of Macular Edema and Branch Retinal Vein Occlusion, sponsored by Retina Associates of Florida, P.A..
- Completed
- Registry status
- Phase 2
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT01247220: Completed Phase 2 study of Macular Edema and Branch Retinal Vein Occlusion, sponsored by Retina Associates of Florida, P.A..
NCT01247220 is a Phase 2 study of Macular Edema and Branch Retinal Vein Occlusion that has completed, run by Retina Associates of Florida, P.A.. The registered enrollment target is 12 participants, below the 179-participant average among 14 other Macular Edema trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01247220, a Phase 2 study of Macular Edema and Branch Retinal Vein Occlusion, has completed, sponsored by Retina Associates of Florida, P.A..
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
Branch retinal vein occlusion is a leading cause of vision loss. Treatment with ranibizumab (vascular endothelial growth factor (VEGF) inhibitor) on a monthly basis has been associated with improved vision results. There is a subgroup of patients with peripheral nonperfusion on ultrawidefield angiography that appears to be more dependent on anti-VEGF treatment. In this trial the investigators compare the gold standard of monthly ranibizumab injections with ranibizumab + peripheral scatter laser to the areas of nonperfusion on angiography. Each group will have monthly injections for the first six months, then as needed by either visual acuity decrease or increased retinal thickness for the subsequent six months. The primary outcome is visual acuity. Secondary outcomes are reduction in optical coherence tomography, and number of ranibizumab injections
Primary Outcome
ETDRS visual acuity
Conditions Studied
Interventions
- DRUG Ranibizumab
- PROCEDURE Peripheral Laser
Study Locations (1)
Florida
- Retina Associates of Florida, P.A. - Tampa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2010-11 |
| Est. Completion | 2014-05 |
| Phase | Phase 2 |
What the finished NCT01247220 record still lists
NCT01247220 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 179-participant average among 14 other Macular Edema trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Macular Edema appearing as the primary indexed condition, and to 2 interventions - of which Ranibizumab is the first listed.
NCT01247220 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT01247220 about?
NCT01247220 is a clinical study titled "REtinal Vein OccLUsion Treatment With Scatter Laser Guided by UWFA in combiNAtion With Ranibizumab Study". Branch retinal vein occlusion is a leading cause of vision loss. Treatment with ranibizumab (vascular endothelial growth factor (VEGF) inhibitor) on a monthly basis has been associated with improved vision results. There is a subgroup of patients with peripheral nonperfusion on ultrawidefield angiog...
What is the current status of trial NCT01247220?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 12 participants. The study started on 2010-11. Estimated completion is 2014-05.
What conditions does trial NCT01247220 study?
This clinical trial studies the following conditions: Macular Edema, Branch Retinal Vein Occlusion.
What interventions are being tested in trial NCT01247220?
The interventions under investigation include: Ranibizumab (DRUG), Peripheral Laser (PROCEDURE).
Who is sponsoring clinical trial NCT01247220?
This trial is sponsored by Retina Associates of Florida, P.A., which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01247220 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01247220's enrollment target sits among peer trials
12 14th of 14 higher than 1 of 14 other Macular Edema trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Macular Edema trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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