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NCT01224704 · ClinicalTrials.gov registry record · NA
Water Deprivation Protocol
A NA study, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- Completed
- Registry status
- NA
- Development phase
- 75
- Enrollment target
NCT01224704 is a NA study that has completed, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 75 participants.
The verdict
NCT01224704, a NA study, has completed, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- COMPLETED
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
Study Summary
Background: \- One area in which obese and lean individuals may be different is how their bodies handle water balance and thirst. Studies done in animals suggest that individuals with greater body fat may tolerate periods without water better than lean animals. Other research has found a link between the ability to tolerate periods without water and increased body weight. Researchers are interested in studying whether the ability to tolerate periods without water and ability to feel thirst might differ in lean versus obese individuals. Objectives: \- To evaluate the effects of water deprivation and feelings of thirst in lean and obese individuals. Eligibility: \- Healthy individuals at least 18 years of age who are either lean (body mass index less than 26 kg/m(2)) or obese (body mass index at least 35 kg/m(2)). Design: * Participants will be screened with a medical history, physical examination, and blood and urine tests. * Participants will spend the entire study (13 days) as inpatients at the National Institutes of Health Clinical Center. * Participants will have the following tests and procedures: * Body composition assessment (using low-level x-rays) to determine the percentage of fat tissue in the body. * Oral glucose tolerance test (similar to that often used to diagnose diabetes). Individuals who are suspected to have diabetes will not be allowed to continue with the study. * High salt infusion test, in which an infusion of saline (salt water) will be given for 2 hours and participants will respond to questions about how hungry and thirsty they feel during the procedure. * Water deprivation test, in which participants will go for 24 hours without water or food and respond to questions about how hungry and thirsty they feel. * 24-hour stay in a metabolic chamber to determine how many calories participants burn in a day. * A series of questionnaires about participants' eating habits, feelings about food, and personal feelings, as well as computer-based
Interventions
- OTHER Hypertonic saline infusion
- OTHER Water deprivation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2010-10-19 |
| Est. Completion | 2019-03-28 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01224704
The ClinicalTrials.gov registry entry for NCT01224704 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 75 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Hypertonic saline infusion is the first listed.
NCT01224704 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01224704 about?
NCT01224704 is a clinical study titled "Water Deprivation Protocol". Background: \- One area in which obese and lean individuals may be different is how their bodies handle water balance and thirst. Studies done in animals suggest that individuals with greater body fat may tolerate periods without water better than lean animals. Other research has found a link betwe...
What is the current status of trial NCT01224704?
This trial is currently completed. It is a NA study. The enrollment target is 75 participants. The study started on 2010-10-19. Estimated completion is 2019-03-28.
What interventions are being tested in trial NCT01224704?
The interventions under investigation include: Hypertonic saline infusion (OTHER), Water deprivation (OTHER).
Who is sponsoring clinical trial NCT01224704?
This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.
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