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NCT01200069 · ClinicalTrials.gov registry record · Phase 4

IV Ibuprofen for Post-Electroconvulsive Therapy Myalgia

A Phase 4 study, sponsored by Rutgers, The State University of New Jersey.

Terminated
Registry status
Phase 4
Development phase
14
Enrollment target

NCT01200069: Clinical Trial Phase 4 study, sponsored by Rutgers, The State University of New Jersey.

NCT01200069 is a Phase 4 study that was terminated before completion, run by Rutgers, The State University of New Jersey. The registered enrollment target is 14 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01200069, a Phase 4 study, was terminated before completion, sponsored by Rutgers, The State University of New Jersey.

TERMINATED
Registry status
Phase 4
Development phase
14 participants
Enrollment target

Study Summary

Post-procedure myalgia (muscle ache) is a well-known and common complication of Electro-convulsive Treatment (ECT). Myalgias are a serious concern of patients and occur in approximately 50% of these cases. The pain is usually described as muscle soreness, similar to that resulting from strenuous exercise. The myalgias typically begin shortly after the procedure, lasting approximately 2-7 days in total. A recent study reported that 89% of patients considered prevention significant and would be willing to pay a median of $33 out of pocket to avoid this side effect. In addition to patient discomfort, myalgias can have a further financial burden if these patients are unable to return to work or resume previous daily activities in the days following the procedure. An agent that could treat and possibly even prevent these myalgias has the potential to be very beneficial to these patients. IV ibuprofen (trade name Caldolor) is a novel therapeutic modality approved by the US Food and Drug Administration (FDA) in June 2009 for the treatment of mild to moderate pain, as an adjunct to opioid analgesics, and for the reduction of fever.

Primary Outcome

subject self reporting rating scale for severity of myalgias utilizing numeric rating scale 0= no pain, 1-3= mild pain, annoyance with little interference with Activities of Daily Living (ADL), 4-6= moderate (interferes significantly with ADL, 7-10 = severe pain unable to perform ADL

Interventions

  • DRUG Placebo infusion
  • DRUG ibuprofen intravenous

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2010-07
Est. Completion 2014-09
Phase Phase 4

Why NCT01200069 stopped before completion

NCT01200069 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo infusion is the first listed.

NCT01200069 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01200069 about?

NCT01200069 is a clinical study titled "IV Ibuprofen for Post-Electroconvulsive Therapy Myalgia". Post-procedure myalgia (muscle ache) is a well-known and common complication of Electro-convulsive Treatment (ECT). Myalgias are a serious concern of patients and occur in approximately 50% of these cases. The pain is usually described as muscle soreness, similar to that resulting from strenuous exe...

What is the current status of trial NCT01200069?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 14 participants. The study started on 2010-07. Estimated completion is 2014-09.

What interventions are being tested in trial NCT01200069?

The interventions under investigation include: Placebo infusion (DRUG), ibuprofen intravenous (DRUG).

Who is sponsoring clinical trial NCT01200069?

This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01200069's enrollment target sits among peer trials

14 1901st of 2000 higher than 91 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01200069, the US trial registry maintained by the National Library of Medicine. NCT01200069 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.