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NCT01192477 · ClinicalTrials.gov registry record · NA
Ozone Cardiovascular Effects in Genetically Susceptible People
A NA study, sponsored by University of Rochester.
- Completed
- Registry status
- NA
- Development phase
- 80
- Enrollment target
NCT01192477: Completed NA study, sponsored by University of Rochester.
NCT01192477 is a NA study that has completed, run by University of Rochester. The registered enrollment target is 80 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01192477, a NA study, has completed, sponsored by University of Rochester.
- COMPLETED
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
Study Summary
Increases in air pollution are associated with increases in deaths from cardiovascular disease, but the investigators know little about how ozone air pollution affects the cardiovascular system. The investigators proposed study will determine the effects of ozone on blood vessel and heart function that could worsen illness in people with underlying heart disease. This will be accomplished by studying healthy volunteers who inhale ozone in a controlled clinical study, and also by studying their exposure to ozone and other pollutants during their normal daily activities. The investigators will study volunteers who may be at increased risk for the effects of ozone because of genetic susceptibility. Understanding the effects of ozone on the heart and circulation can help establish appropriate air pollution standards, and provide strategies to protect the most susceptible people.
Primary Outcome
We hypothesize that systemic vascular effects of exposure to ozone will be reflected in reductions in arterial blood nitrite or its A/V gradient. This will require simultaneous collection of venous and arterial blood.
Interventions
- OTHER Ozone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2011-05 |
| Est. Completion | 2012-08 |
| Phase | NA |
What the finished NCT01192477 record still lists
NCT01192477 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 1 intervention - of which Ozone is the first listed.
NCT01192477 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01192477 about?
NCT01192477 is a clinical study titled "Ozone Cardiovascular Effects in Genetically Susceptible People". Increases in air pollution are associated with increases in deaths from cardiovascular disease, but the investigators know little about how ozone air pollution affects the cardiovascular system. The investigators proposed study will determine the effects of ozone on blood vessel and heart function t...
What is the current status of trial NCT01192477?
This trial is currently completed. It is a NA study. The enrollment target is 80 participants. The study started on 2011-05. Estimated completion is 2012-08.
What interventions are being tested in trial NCT01192477?
The interventions under investigation include: Ozone (OTHER).
Who is sponsoring clinical trial NCT01192477?
This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01192477's enrollment target sits among peer trials
80 994th of 2000 higher than 941 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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