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NCT01187901 · ClinicalTrials.gov registry record · Phase 2

A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients

A Phase 2 study of Adenomatous Polyposis Coli, sponsored by University of Utah.

Completed
Registry status
Phase 2
Development phase
92
Enrollment target
1
Study location

NCT01187901 is a Phase 2 study of Adenomatous Polyposis Coli that has completed, run by University of Utah. The registered enrollment target is 92 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT01187901, a Phase 2 study of Adenomatous Polyposis Coli, has completed, sponsored by University of Utah.

COMPLETED
Registry status
Phase 2
Development phase
92 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine in a randomized, placebo-controlled, phase II trial if the combination of sulindac and erlotinib causes a significant regression of duodenal and colorectal adenomas in familial adenomatous polyposis (FAP) and attenuated FAP (AFAP) patients.

Conditions Studied

Interventions

  • DRUG Erlotinib
  • DRUG Sulindac
  • DRUG Placebo A
  • DRUG Placebo B

Study Locations (1)

Utah

  • Huntsman Cancer Institute - Salt Lake City

Trial Details

FieldValue
Enrollment Target 92 participants
Start Date 2010-04
Est. Completion 2014-07
Phase Phase 2

Sponsor

University of Utah

818 total trials

What the Registry Record Tells You About NCT01187901

The ClinicalTrials.gov registry entry for NCT01187901 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 92 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Adenomatous Polyposis Coli appearing as the primary indexed condition, and to 4 interventions - of which Erlotinib is the first listed.

NCT01187901 reports 1 study location spanning 1 distinct geographic area - top geographies include Utah.

Frequently Asked Questions

What is clinical trial NCT01187901 about?

NCT01187901 is a clinical study titled "A Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients". The purpose of this study is to determine in a randomized, placebo-controlled, phase II trial if the combination of sulindac and erlotinib causes a significant regression of duodenal and colorectal adenomas in familial adenomatous polyposis (FAP) and attenuated FAP (AFAP) patients.

What is the current status of trial NCT01187901?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 92 participants. The study started on 2010-04. Estimated completion is 2014-07.

What conditions does trial NCT01187901 study?

This clinical trial studies the following conditions: Adenomatous Polyposis Coli.

What interventions are being tested in trial NCT01187901?

The interventions under investigation include: Erlotinib (DRUG), Sulindac (DRUG), Placebo A (DRUG), Placebo B (DRUG).

Who is sponsoring clinical trial NCT01187901?

This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01187901 being conducted?

This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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