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NCT01164215 · ClinicalTrials.gov registry record · Phase 1

Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy

A Phase 1 study, sponsored by UNC Lineberger Comprehensive Cancer Center.

Completed
Registry status
Phase 1
Development phase
76
Enrollment target

NCT01164215 is a Phase 1 study that has completed, run by UNC Lineberger Comprehensive Cancer Center. The registered enrollment target is 76 participants.

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The verdict

NCT01164215, a Phase 1 study, has completed, sponsored by UNC Lineberger Comprehensive Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
76 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as fluorouracil, oxaliplatin, and leucovorin calcium, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug, combination chemotherapy, may kill more tumor cells. Studying samples of blood in the laboratory from patients with cancer receiving fluorouracil in combination with oxaliplatin and leucovorin calcium may help doctors learn how fluorouracil works in the body and how patients will respond to treatment. PURPOSE: This phase I trial is studying biomarker-guided fluorouracil in treating patients with colorectal cancer receiving combination chemotherapy.

Interventions

  • DRUG oxaliplatin
  • DRUG fluorouracil
  • DRUG leucovorin

Trial Details

FieldValue
Enrollment Target 76 participants
Start Date 2010-02
Est. Completion 2013-09
Phase Phase 1

What the Registry Record Tells You About NCT01164215

The ClinicalTrials.gov registry entry for NCT01164215 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 76 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is UNC Lineberger Comprehensive Cancer Center, which has 366 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which oxaliplatin is the first listed.

NCT01164215 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01164215 about?

NCT01164215 is a clinical study titled "Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy". RATIONALE: Drugs used in chemotherapy, such as fluorouracil, oxaliplatin, and leucovorin calcium, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug, combination chemotherapy, may kill more tumor cells. S...

What is the current status of trial NCT01164215?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 76 participants. The study started on 2010-02. Estimated completion is 2013-09.

What interventions are being tested in trial NCT01164215?

The interventions under investigation include: oxaliplatin (DRUG), fluorouracil (DRUG), leucovorin (DRUG).

Who is sponsoring clinical trial NCT01164215?

This trial is sponsored by UNC Lineberger Comprehensive Cancer Center, which has 366 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.