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NCT01157845 · ClinicalTrials.gov registry record · Phase 3
Use of Methacetin Breath Test to Predict Liver Failure in Patients With Cirrhosis
A Phase 3 study of Cirrhosis, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- Phase 3
- Development phase
- 165
- Enrollment target
- 4
- Study locations
NCT01157845: Completed Phase 3 study of Cirrhosis, sponsored by Virginia Commonwealth University.
NCT01157845 is a Phase 3 study of Cirrhosis that has completed, run by Virginia Commonwealth University. The registered enrollment target is 165 participants, below the 90,406-participant average among 53 other Cirrhosis trials with a reported enrollment target (100% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01157845, a Phase 3 study of Cirrhosis, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 165 participants
- Enrollment target
- 4
- Study locations
Study Summary
The methacetin breath test (MBT) is a non-invasive liver function test which measures the ability of the liver to metabolize a tracer dose of a compound to carbon dioxide, which is exhaled. The study hypothesis is that measurement of the MBT will allow earlier detection of a decline in liver function in patients with cirrhosis who are awaiting liver transplantation.
Primary Outcome
Patient dies of liver-related causes within 1 year of study entry
Conditions Studied
Interventions
- DEVICE BreathID (Methacetin breath test)
Study Locations (4)
Michigan
- Henry Ford Health System - Detroit
South Carolina
- Medical University of South Carolina - Charleston
Virginia
- Virginia Commonwealth University Medical Center - Richmond
Israel
- Hadassah Medical Center - Jerusalem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 165 participants |
| Start Date | 2010-03 |
| Est. Completion | 2012-07 |
| Phase | Phase 3 |
What the finished NCT01157845 record still lists
NCT01157845 is an interventional study that assigns participants to a tested intervention. The registered 165 participants enrollment target is mid-sized for trials with a published cap, below the 90,406-participant average among 53 other Cirrhosis trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Cirrhosis appearing as the primary indexed condition, and to 1 intervention - of which BreathID (Methacetin breath test) is the first listed.
NCT01157845 reports a single indexed study location in Michigan, South Carolina, Virginia.
Frequently Asked Questions
What is clinical trial NCT01157845 about?
NCT01157845 is a clinical study titled "Use of Methacetin Breath Test to Predict Liver Failure in Patients With Cirrhosis". The methacetin breath test (MBT) is a non-invasive liver function test which measures the ability of the liver to metabolize a tracer dose of a compound to carbon dioxide, which is exhaled. The study hypothesis is that measurement of the MBT will allow earlier detection of a decline in liver functio...
What is the current status of trial NCT01157845?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 165 participants. The study started on 2010-03. Estimated completion is 2012-07.
What conditions does trial NCT01157845 study?
This clinical trial studies the following conditions: Cirrhosis.
What interventions are being tested in trial NCT01157845?
The interventions under investigation include: BreathID (Methacetin breath test) (DEVICE).
Who is sponsoring clinical trial NCT01157845?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01157845 being conducted?
This trial has 4 study locations across Michigan, South Carolina, Virginia, Israel. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cirrhosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01157845's enrollment target sits among peer trials
165 15th of 53 higher than 39 of 53 other Cirrhosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cirrhosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
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