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NCT01116440 · ClinicalTrials.gov registry record · Phase 2
A Safety & Efficacy Study of BGS649 in Women With Refractory Endometriosis
A Phase 2 study, sponsored by Mereo BioPharma.
- Terminated
- Registry status
- Phase 2
- Development phase
- 27
- Enrollment target
NCT01116440: Clinical Trial Phase 2 study, sponsored by Mereo BioPharma.
NCT01116440 is a Phase 2 study that was terminated before completion, run by Mereo BioPharma. The registered enrollment target is 27 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01116440, a Phase 2 study, was terminated before completion, sponsored by Mereo BioPharma.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 27 participants
- Enrollment target
Study Summary
The purpose of this study is to determine efficacy, safety, tolerability and pharmacokinetics of multiple doses of BGS649 with concurrent daily administration of combined oral contraception in patients with refractory endometriosis
Primary Outcome
Mean change from baseline to Month 3 (Week 12) in Number Rating Scale pelvic pain score. The Numeric Rating Scale is a scale between 0 and 10 where 0 is no pain and 10 is the worse pain you can imagine.
Interventions
- DRUG Placebo
- DRUG BGS649
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2010-04-15 |
| Est. Completion | 2012-03-21 |
| Phase | Phase 2 |
Why NCT01116440 stopped before completion
NCT01116440 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01116440 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01116440 about?
NCT01116440 is a clinical study titled "A Safety & Efficacy Study of BGS649 in Women With Refractory Endometriosis". The purpose of this study is to determine efficacy, safety, tolerability and pharmacokinetics of multiple doses of BGS649 with concurrent daily administration of combined oral contraception in patients with refractory endometriosis
What is the current status of trial NCT01116440?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2010-04-15. Estimated completion is 2012-03-21.
What interventions are being tested in trial NCT01116440?
The interventions under investigation include: Placebo (DRUG), BGS649 (DRUG).
Who is sponsoring clinical trial NCT01116440?
This trial is sponsored by Mereo BioPharma, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01116440's enrollment target sits among peer trials
27 1697th of 2000 higher than 293 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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