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NCT01114516 · ClinicalTrials.gov registry record · NA
Multifactorial Approach to Emergent Cerclage
A NA study of Cervical Insufficiency, sponsored by Northwestern University.
- Completed
- Registry status
- NA
- Development phase
- 53
- Enrollment target
- 1
- Study location
NCT01114516: Completed NA study of Cervical Insufficiency, sponsored by Northwestern University.
NCT01114516 is a NA study of Cervical Insufficiency that has completed, run by Northwestern University. The registered enrollment target is 53 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01114516, a NA study of Cervical Insufficiency, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- NA
- Development phase
- 53 participants
- Enrollment target
- 1
- Study location
Study Summary
Though cervical insufficiency is a common cause of second trimester pregnancy loss, the placement of an emergent cerclage in these patients is thought to improve perinatal outcomes. It is unknown whether the use of tocolytics and antibiotics prolongs pregnancies complicated by need for emergent cerclage. The objective is to determine whether administration of peri-operative antibiotics and indomethacin to patients receiving emergent cerclages for cervical insufficiency increases latency period to delivery compared with patients receiving emergent cerclage alone.
Primary Outcome
Median gestational latency achieved Between Cerclage Placement and Time of Delivery
Conditions Studied
Interventions
- DRUG Indomethacin and antibiotics (cefazolin or clindamycin)
Study Locations (1)
Illinois
- Prentice Women's Hospital - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 53 participants |
| Start Date | 2010-03 |
| Est. Completion | 2014-03 |
| Phase | NA |
What the finished NCT01114516 record still lists
NCT01114516 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 53 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Cervical Insufficiency appearing as the primary indexed condition, and to 1 intervention - of which Indomethacin and antibiotics (cefazolin or clindamycin) is the first listed.
NCT01114516 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT01114516 about?
NCT01114516 is a clinical study titled "Multifactorial Approach to Emergent Cerclage". Though cervical insufficiency is a common cause of second trimester pregnancy loss, the placement of an emergent cerclage in these patients is thought to improve perinatal outcomes. It is unknown whether the use of tocolytics and antibiotics prolongs pregnancies complicated by need for emergent cerc...
What is the current status of trial NCT01114516?
This trial is currently completed. It is a NA study. The enrollment target is 53 participants. The study started on 2010-03. Estimated completion is 2014-03.
What conditions does trial NCT01114516 study?
This clinical trial studies the following conditions: Cervical Insufficiency.
What interventions are being tested in trial NCT01114516?
The interventions under investigation include: Indomethacin and antibiotics (cefazolin or clindamycin) (DRUG).
Who is sponsoring clinical trial NCT01114516?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01114516 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01114516's enrollment target sits among peer trials
53 1271st of 2000 higher than 729 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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