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NCT01082874 · ClinicalTrials.gov registry record · Phase 3
PeriOperative ISchemic Evaluation-2 Trial
A Phase 3 study of Cardiovascular Disease, sponsored by Hamilton Health Sciences Corporation.
- Completed
- Registry status
- Phase 3
- Development phase
- 10,010
- Enrollment target
- 20
- Study locations
NCT01082874 is a Phase 3 study of Cardiovascular Disease that has completed, run by Hamilton Health Sciences Corporation. The registered enrollment target is 10,010 participants, above the 2,640-participant average among 136 other Cardiovascular Disease trials with a reported enrollment target (279% higher). The trial reports 20 study locations across 4 states.
The verdict
NCT01082874, a Phase 3 study of Cardiovascular Disease, has completed, sponsored by Hamilton Health Sciences Corporation.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 10,010 participants
- Enrollment target
- 20
- Study locations
Study Summary
Major surgeries not involving the heart are common, and major heart problems during or after such surgeries represent a large population health problem. Few treatments to prevent heart problems around the time of surgery have been tested. There is encouraging data suggesting that small doses of Acetyl-Salicylic Acid (ASA) and Clonidine, which are two medications, given individually for a short period before and after major surgeries may prevent major heart problems. The POISE-2 Trial is a large international study to test if ASA and Clonidine can prevent heart attacks and deaths from heart problems around the time of surgery.
Conditions Studied
Interventions
- DRUG Active Clonidine
- DRUG Placebo Clonidine
- DRUG Active ASA
- DRUG Placebo ASA
Study Locations (20)
Other
- National Coordination Office - Rosario
- National Coordination Office - Vienna
- National Coordination Office - Brussels
- National Coordination Office - São Paulo
- National Coordination Office - Santiago
- National Coordination Office - Bucamaranga
- National Coordination Office - Herlev
- National Coordination Office - Boulogne-Billancourt
- National Coordination Office - Bonn
- National Coordination Office - Hong Kong
- National Coordination Office - Bangalore
- National Coordination Office - Milan
- National Coordination Office - Kuala Lumpur
- National Coordination Office - Auckland
- National Coordination Office - Islamabad
- National Coordination Office - Lima
- National Coordination Office - Durban
Ohio
- National Coordination Office - Cleveland
Victoria
- National Coordination Office Australia and New Zealand - Parkville
Ontario
- National Coordination Office - Hamilton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10,010 participants |
| Start Date | 2010-07 |
| Est. Completion | 2015-01 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01082874
The ClinicalTrials.gov registry entry for NCT01082874 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 10,010 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 2,640-participant average among 136 other Cardiovascular Disease trials with a reported enrollment target (279% higher). The listed sponsor is Hamilton Health Sciences Corporation, which has 5 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Cardiovascular Disease appearing as the primary indexed condition, and to 4 interventions - of which Active Clonidine is the first listed.
NCT01082874 reports 20 study locations spanning 4 distinct geographic areas - top geographies include Other, Ohio, Victoria.
Frequently Asked Questions
What is clinical trial NCT01082874 about?
NCT01082874 is a clinical study titled "PeriOperative ISchemic Evaluation-2 Trial". Major surgeries not involving the heart are common, and major heart problems during or after such surgeries represent a large population health problem. Few treatments to prevent heart problems around the time of surgery have been tested. There is encouraging data suggesting that small doses of Acet...
What is the current status of trial NCT01082874?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 10,010 participants. The study started on 2010-07. Estimated completion is 2015-01.
What conditions does trial NCT01082874 study?
This clinical trial studies the following conditions: Cardiovascular Disease.
What interventions are being tested in trial NCT01082874?
The interventions under investigation include: Active Clonidine (DRUG), Placebo Clonidine (DRUG), Active ASA (DRUG), Placebo ASA (DRUG).
Who is sponsoring clinical trial NCT01082874?
This trial is sponsored by Hamilton Health Sciences Corporation, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01082874 being conducted?
This trial has 20 study locations across Ohio, Victoria, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.