Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01054872 · ClinicalTrials.gov registry record · Phase 1

Examining the Role of Genetics in Determining the Immune Response to an HIV Vaccine in HIV-Uninfected Adult Twins

A Phase 1 study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
8
Enrollment target
2
Study locations

NCT01054872: Completed Phase 1 study of HIV Infections, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT01054872 is a Phase 1 study of HIV Infections that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 8 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01054872, a Phase 1 study of HIV Infections, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
8 participants
Enrollment target
2
Study locations

Study Summary

The purpose of this study is to examine the role of genetics in determining the immune response to an HIV vaccine in pairs of HIV-uninfected twins.

Conditions Studied

Interventions

  • BIOLOGICAL HIV-1 DNA plasmid vaccine
  • BIOLOGICAL HIV-1 recombinant Ad5 vaccine

Study Locations (2)

Massachusetts

  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS) - Boston

Washington

  • Seattle Vaccine and Prevention CRS - Seattle

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2010-01
Est. Completion 2016-06
Phase Phase 1

What the finished NCT01054872 record still lists

NCT01054872 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (98% lower).

The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 2 interventions - of which HIV-1 DNA plasmid vaccine is the first listed.

NCT01054872 reports a single indexed study location in Massachusetts, Washington.

Frequently Asked Questions

What is clinical trial NCT01054872 about?

NCT01054872 is a clinical study titled "Examining the Role of Genetics in Determining the Immune Response to an HIV Vaccine in HIV-Uninfected Adult Twins". The purpose of this study is to examine the role of genetics in determining the immune response to an HIV vaccine in pairs of HIV-uninfected twins.

What is the current status of trial NCT01054872?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2010-01. Estimated completion is 2016-06.

What conditions does trial NCT01054872 study?

This clinical trial studies the following conditions: HIV Infections.

What interventions are being tested in trial NCT01054872?

The interventions under investigation include: HIV-1 DNA plasmid vaccine (BIOLOGICAL), HIV-1 recombinant Ad5 vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT01054872?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01054872 being conducted?

This trial has 2 study locations across Massachusetts, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV Infections

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01054872's enrollment target sits among peer trials

8 533rd of 542 higher than 8 of 542 other HIV Infections trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01054872, the US trial registry maintained by the National Library of Medicine. NCT01054872 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.