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NCT01053156 · ClinicalTrials.gov registry record · NA

Trial of Minocycline to Treat Children With Fragile X Syndrome

A NA study of Fragile X Syndrome, sponsored by University of California, Davis.

Completed
Registry status
NA
Development phase
66
Enrollment target
1
Study location

NCT01053156 is a NA study of Fragile X Syndrome that has completed, run by University of California, Davis. The registered enrollment target is 66 participants, below the 98-participant average among 16 other Fragile X Syndrome trials with a reported enrollment target (33% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01053156, a NA study of Fragile X Syndrome, has completed, sponsored by University of California, Davis.

COMPLETED
Registry status
NA
Development phase
66 participants
Enrollment target
1
Study location

Study Summary

This is a single center study at the UC Davis MIND Institute in patients age 3.5-16 years of age with fragile X syndrome (FXS), funded by a National Fragile X Foundation Grant. It is a controlled trial of minocycline, an antibiotic commonly used in children for infection or for treatment of neurodegenerative disorders. We are investigating its use in FXS because it lowers matrix metalloproteinase 9 (MMP9) levels, which are high in FXS, and it also strengthens brain connections in the animal models of FXS. We hypothesize that minocycline will likely be helpful for language, behavior and/or cognition in fragile X patients.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG minocycline hydrochloride

Study Locations (1)

California

  • M.I.N.D. Institute at University of California at Davis Medical Center - Sacramento

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2010-01
Est. Completion 2011-12
Phase NA

Sponsor

University of California, Davis

657 total trials

What the Registry Record Tells You About NCT01053156

The ClinicalTrials.gov registry entry for NCT01053156 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 66 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 98-participant average among 16 other Fragile X Syndrome trials with a reported enrollment target (33% lower). The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Fragile X Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT01053156 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT01053156 about?

NCT01053156 is a clinical study titled "Trial of Minocycline to Treat Children With Fragile X Syndrome". This is a single center study at the UC Davis MIND Institute in patients age 3.5-16 years of age with fragile X syndrome (FXS), funded by a National Fragile X Foundation Grant. It is a controlled trial of minocycline, an antibiotic commonly used in children for infection or for treatment of neurodeg...

What is the current status of trial NCT01053156?

This trial is currently completed. It is a NA study. The enrollment target is 66 participants. The study started on 2010-01. Estimated completion is 2011-12.

What conditions does trial NCT01053156 study?

This clinical trial studies the following conditions: Fragile X Syndrome.

What interventions are being tested in trial NCT01053156?

The interventions under investigation include: Placebo (DRUG), minocycline hydrochloride (DRUG).

Who is sponsoring clinical trial NCT01053156?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01053156 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.