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NCT01007071 · ClinicalTrials.gov registry record · Phase 3
Effects of Growth Hormone on Cognition and Cerebral Metabolism in Adults With Growth Hormone Deficiency
A Phase 3 study, sponsored by Stanford University.
- Completed
- Registry status
- Phase 3
- Development phase
- 11
- Enrollment target
NCT01007071: Completed Phase 3 study, sponsored by Stanford University.
NCT01007071 is a Phase 3 study that has completed, run by Stanford University. The registered enrollment target is 11 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01007071, a Phase 3 study, has completed, sponsored by Stanford University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 11 participants
- Enrollment target
Study Summary
Patients with Growth hormone (GH) deficiency often report impaired quality of life and difficulty with mental functioning. It has been suggested that GH replacement in such patients leads to improvement in cognitive function. The aim of this study is to elucidate the effects of GH replacement in patients with GH deficiency on cognitive function using structural and functional neuroimaging and cognitive testing.
Primary Outcome
Functional MRI scans were to be performed at baseline and at 16 weeks. Changes in functional connectivity before and after 16 weeks of treatment were analyzed. The analysis involved approximately 40,000 paired sample t-tests. The dependent variable here for each subject is the correlation between the BOLD timeseries in the seed region (posterior cingulate cortex) and the BOLD timeseries in a given, standard space, brain voxel. This paired-sample t-test is run, separately, for every voxel in the
Interventions
- DRUG Placebo
- DRUG Human Growth Hormone (1-134)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2009-11-01 |
| Est. Completion | 2012-12-12 |
| Phase | Phase 3 |
What the finished NCT01007071 record still lists
NCT01007071 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01007071 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01007071 about?
NCT01007071 is a clinical study titled "Effects of Growth Hormone on Cognition and Cerebral Metabolism in Adults With Growth Hormone Deficiency". Patients with Growth hormone (GH) deficiency often report impaired quality of life and difficulty with mental functioning. It has been suggested that GH replacement in such patients leads to improvement in cognitive function. The aim of this study is to elucidate the effects of GH replacement in pat...
What is the current status of trial NCT01007071?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 11 participants. The study started on 2009-11-01. Estimated completion is 2012-12-12.
What interventions are being tested in trial NCT01007071?
The interventions under investigation include: Placebo (DRUG), Human Growth Hormone (1-134) (DRUG).
Who is sponsoring clinical trial NCT01007071?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01007071's enrollment target sits among peer trials
11 1989th of 2000 higher than 12 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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