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NCT01003301 · ClinicalTrials.gov registry record · Phase 2

The Effects of Omalizumab (Anti-IgE) on the Late-phase Response to Nasal Allergen Challenge

A Phase 2 study of Cat Allergy, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 2
Development phase
19
Enrollment target
1
Study location

NCT01003301 is a Phase 2 study of Cat Allergy that has completed, run by Johns Hopkins University. The registered enrollment target is 19 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT01003301, a Phase 2 study of Cat Allergy, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 2
Development phase
19 participants
Enrollment target
1
Study location

Study Summary

This research is being done to study the effects of the drug omalizumab (Xolair) in people with cat allergies. The investigators will use omalizumab to study changes in the cells in the nose, cells in the blood and cells in the skin that cause allergies. The investigators will compare the changes in the nose to changes in the skin and blood cells. Objective: To test the hypothesis that treatment with omalizumab will decrease the nasal allergen challenge late-phase eosinophil count in nasal brushings at the time when blood basophils have become hypo-responsive to in vitro allergen exposure.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Omalizumab

Study Locations (1)

Maryland

  • Johns Hopkins Asthma and Allergy Center - Baltimore

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2009-10
Est. Completion 2013-09
Phase Phase 2

Sponsor

Johns Hopkins University

1,448 total trials

What the Registry Record Tells You About NCT01003301

The ClinicalTrials.gov registry entry for NCT01003301 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cat Allergy appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT01003301 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT01003301 about?

NCT01003301 is a clinical study titled "The Effects of Omalizumab (Anti-IgE) on the Late-phase Response to Nasal Allergen Challenge". This research is being done to study the effects of the drug omalizumab (Xolair) in people with cat allergies. The investigators will use omalizumab to study changes in the cells in the nose, cells in the blood and cells in the skin that cause allergies. The investigators will compare the changes in...

What is the current status of trial NCT01003301?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 2009-10. Estimated completion is 2013-09.

What conditions does trial NCT01003301 study?

This clinical trial studies the following conditions: Cat Allergy.

What interventions are being tested in trial NCT01003301?

The interventions under investigation include: Placebo (DRUG), Omalizumab (DRUG).

Who is sponsoring clinical trial NCT01003301?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01003301 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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