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NCT00998946 · ClinicalTrials.gov registry record · Phase 2

Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

A Phase 2 study, sponsored by Spectrum Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
29
Enrollment target

NCT00998946 is a Phase 2 study that has completed, run by Spectrum Pharmaceuticals. The registered enrollment target is 29 participants.

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The verdict

NCT00998946, a Phase 2 study, has completed, sponsored by Spectrum Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
29 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether pralatrexate, given with vitamin B12 and folic acid, is effective in the treatment of relapsed or refractory B-cell Non-Hodgkin's lymphoma (NHL). The study will also investigate the safety of pralatrexate with vitamin B12 and folic acid in this participant population. Additionally, this study includes the collection of blood samples to investigate the pharmacokinetics (PK) of pralatrexate in this participant population (PK is the activity of a drug in the body over a period of time, including how the drug is absorbed, distributed in the body, localized in the tissues, and excreted from the body).

Interventions

  • DIETARY_SUPPLEMENT Vitamin B12
  • DRUG Pralatrexate
  • DIETARY_SUPPLEMENT Folic Acid

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2009-09
Est. Completion 2012-08
Phase Phase 2

Sponsor

Spectrum Pharmaceuticals

52 total trials

What the Registry Record Tells You About NCT00998946

The ClinicalTrials.gov registry entry for NCT00998946 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Spectrum Pharmaceuticals, which has 52 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Vitamin B12 is the first listed.

NCT00998946 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00998946 about?

NCT00998946 is a clinical study titled "Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma". The purpose of this study is to determine whether pralatrexate, given with vitamin B12 and folic acid, is effective in the treatment of relapsed or refractory B-cell Non-Hodgkin's lymphoma (NHL). The study will also investigate the safety of pralatrexate with vitamin B12 and folic acid in this parti...

What is the current status of trial NCT00998946?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2009-09. Estimated completion is 2012-08.

What interventions are being tested in trial NCT00998946?

The interventions under investigation include: Vitamin B12 (DIETARY_SUPPLEMENT), Pralatrexate (DRUG), Folic Acid (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT00998946?

This trial is sponsored by Spectrum Pharmaceuticals, which has 52 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.