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NCT00993460 · ClinicalTrials.gov registry record
Study of Changes in Skeletal Muscle After Caloric Restriction
A clinical trial of Obesity, sponsored by Vanderbilt University.
- Active
- Registry status
- 24
- Enrollment target
- 1
- Study location
NCT00993460: Active study of Obesity, sponsored by Vanderbilt University.
NCT00993460 is a study of Obesity that is active but no longer recruiting, run by Vanderbilt University. The registered enrollment target is 24 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00993460, a study of Obesity, is active but no longer recruiting, sponsored by Vanderbilt University.
- ACTIVE NOT RECRUITING
- Registry status
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
Research has shown that fat stored within muscles affects the muscle's sensitivity to insulin and ability to handle blood glucose. The purpose of this study is to examine the effects of weight loss surgery-induced caloric restriction on the accumulation and types of fats within skeletal muscle, as well as the effects of such caloric restriction on insulin sensitivity and inflammatory responses in skeletal muscle. The investigator proposes that caloric restriction will result in decreases in diacylglycerols enriched with saturated fat and increases in diacylglycerols enriched with monounsaturated fats.
Primary Outcome
Muscle lipid will be analyzed by LC-MS/MS
Conditions Studied
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2011-03 |
| Est. Completion | 2026-11 |
What the registry record for NCT00993460 still lists
NCT00993460 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 0 interventions.
NCT00993460 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT00993460 about?
NCT00993460 is a clinical study titled "Study of Changes in Skeletal Muscle After Caloric Restriction". Research has shown that fat stored within muscles affects the muscle's sensitivity to insulin and ability to handle blood glucose. The purpose of this study is to examine the effects of weight loss surgery-induced caloric restriction on the accumulation and types of fats within skeletal muscle, as w...
What is the current status of trial NCT00993460?
This trial is currently active not recruiting. The enrollment target is 24 participants. The study started on 2011-03. Estimated completion is 2026-11.
What conditions does trial NCT00993460 study?
This clinical trial studies the following conditions: Obesity.
Who is sponsoring clinical trial NCT00993460?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00993460 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00993460's enrollment target sits among peer trials
24 909th of 1053 higher than 127 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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