Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00992446 · ClinicalTrials.gov registry record · Phase 2

Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma

A Phase 2 study, sponsored by Fred Hutchinson Cancer Center.

Completed
Registry status
Phase 2
Development phase
27
Enrollment target

NCT00992446 is a Phase 2 study that has completed, run by Fred Hutchinson Cancer Center. The registered enrollment target is 27 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00992446, a Phase 2 study, has completed, sponsored by Fred Hutchinson Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
27 participants
Enrollment target

Study Summary

This phase II trial studies the side effects and how well bortezomib and vorinostat work in treating patients with non-Hodgkin lymphoma (NHL) after patients' own stem cell (autologous) transplant. Bortezomib and vorinostat in the laboratory may stop the growth of lymphoma cells and make them more likely to die by blocking some of the enzymes needed for cell growth. Giving bortezomib together with vorinostat after an autologous stem cell transplant may thus kill lymphoma cells that remain after transplant.

Interventions

  • DRUG Etoposide
  • DRUG Cytarabine
  • DRUG Carmustine
  • DRUG Bortezomib
  • PROCEDURE Autologous Hematopoietic Stem Cell Transplantation

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2010-09-02
Est. Completion 2019-10-29
Phase Phase 2

Sponsor

Fred Hutchinson Cancer Center

483 total trials

What the Registry Record Tells You About NCT00992446

The ClinicalTrials.gov registry entry for NCT00992446 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Fred Hutchinson Cancer Center, which has 483 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Etoposide is the first listed.

NCT00992446 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00992446 about?

NCT00992446 is a clinical study titled "Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma". This phase II trial studies the side effects and how well bortezomib and vorinostat work in treating patients with non-Hodgkin lymphoma (NHL) after patients' own stem cell (autologous) transplant. Bortezomib and vorinostat in the laboratory may stop the growth of lymphoma cells and make them more li...

What is the current status of trial NCT00992446?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2010-09-02. Estimated completion is 2019-10-29.

What interventions are being tested in trial NCT00992446?

The interventions under investigation include: Etoposide (DRUG), Cytarabine (DRUG), Carmustine (DRUG), Bortezomib (DRUG), Autologous Hematopoietic Stem Cell Transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT00992446?

This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.