Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00981149 · ClinicalTrials.gov registry record · NA
Duloxetine for Treatment of Painful Temporomandibular Joint Disorder
A NA study of Temporomandibular Joint Disorders, sponsored by University of Maryland, Baltimore.
- Completed
- Registry status
- NA
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT00981149: Completed NA study of Temporomandibular Joint Disorders, sponsored by University of Maryland, Baltimore.
NCT00981149 is a NA study of Temporomandibular Joint Disorders that has completed, run by University of Maryland, Baltimore. The registered enrollment target is 24 participants, below the 449-participant average among 3 other Temporomandibular Joint Disorders trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00981149, a NA study of Temporomandibular Joint Disorders, has completed, sponsored by University of Maryland, Baltimore.
- COMPLETED
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
Temporomandibular joint disorders (TMJD) are a family of musculoskeletal disorders that represent the most common chronic orofacial pain condition. TMJD is associated with persistent pain in the region of the temporomandibular joint and muscles of the head and neck. The purpose of this study is to test duloxetine (Cymbalta) as a potential treatment for chronic facial pain. Duloxetine is FDA approved as an antidepressant and for the chronic pain conditions of fibromyalgia and diabetic neuropathy. Chronic facial pain may be linked to Temporomandibular Joint Disorder (TMJD) which currently has no standard treatment.
Primary Outcome
Measurements from zero to 100 with 100 being the worst pain by Visual Analog Scale (VAS).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG duloxetine
Study Locations (1)
Maryland
- University of Maryland Dental School - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2009-05 |
| Est. Completion | 2011-12 |
| Phase | NA |
What the finished NCT00981149 record still lists
NCT00981149 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 449-participant average among 3 other Temporomandibular Joint Disorders trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Temporomandibular Joint Disorders appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00981149 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00981149 about?
NCT00981149 is a clinical study titled "Duloxetine for Treatment of Painful Temporomandibular Joint Disorder". Temporomandibular joint disorders (TMJD) are a family of musculoskeletal disorders that represent the most common chronic orofacial pain condition. TMJD is associated with persistent pain in the region of the temporomandibular joint and muscles of the head and neck. The purpose of this study is to t...
What is the current status of trial NCT00981149?
This trial is currently completed. It is a NA study. The enrollment target is 24 participants. The study started on 2009-05. Estimated completion is 2011-12.
What conditions does trial NCT00981149 study?
This clinical trial studies the following conditions: Temporomandibular Joint Disorders.
What interventions are being tested in trial NCT00981149?
The interventions under investigation include: Placebo (DRUG), duloxetine (DRUG).
Who is sponsoring clinical trial NCT00981149?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00981149 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Temporomandibular Joint Disorders
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02331979 · 24 participants · NA
Improving Bladder Function in SCI by Neuromodulation
- NCT03096197 · 24 participants · NA
Exoskeleton and Spinal Cord Stimulation for SCI
- NCT03223922 · 24 participants · NA
Neurocognitive Functioning With Genu-Sparing Whole Brain Radiation Therapy for Brain Metastases
- NCT03326921 · 24 participants · Phase 1
HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia