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NCT00952276 · ClinicalTrials.gov registry record · Phase 2

A Study of Different Formulations of an Adjuvanted A/H1N1 Pandemic Vaccine in Healthy Adults and the Elderly

A Phase 2 study, sponsored by Sanofi.

Completed
Registry status
Phase 2
Development phase
548
Enrollment target

NCT00952276: Completed Phase 2 study, sponsored by Sanofi.

NCT00952276 is a Phase 2 study that has completed, run by Sanofi. The registered enrollment target is 548 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (312% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00952276, a Phase 2 study, has completed, sponsored by Sanofi.

COMPLETED
Registry status
Phase 2
Development phase
548 participants
Enrollment target

Study Summary

The purpose of the study is to evaluate different doses of the Influenza A/H1N1 pandemic vaccine in adults and the elderly. Primary Objectives: * To describe the immunogenicity of the candidate vaccines after a single injection. * To describe the safety of the candidate vaccines after a single injection.

Primary Outcome

Antibodies to vaccine were measured using the Hemagglutinin Inhibition (HAI) assay. Detectable anti HA antibody titer was defined as titers ≥ 10 (1/dilution) on Day 0 and Day 21 post-vaccination.

Interventions

  • BIOLOGICAL Monovalent Subvirion A/H1N1 influenza vaccine with adjuvant
  • BIOLOGICAL Monovalent Subvirion A/H1N1 influenza vaccine
  • BIOLOGICAL Normal saline solution

Trial Details

FieldValue
Enrollment Target 548 participants
Start Date 2009-10
Est. Completion 2011-03
Phase Phase 2
Sanofi

713 total trials

What the finished NCT00952276 record still lists

NCT00952276 is an interventional study that assigns participants to a tested intervention. The registered 548 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (312% higher).

The record links to 0 conditions, and to 3 interventions - of which Monovalent Subvirion A/H1N1 influenza vaccine with adjuvant is the first listed.

NCT00952276 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00952276 about?

NCT00952276 is a clinical study titled "A Study of Different Formulations of an Adjuvanted A/H1N1 Pandemic Vaccine in Healthy Adults and the Elderly". The purpose of the study is to evaluate different doses of the Influenza A/H1N1 pandemic vaccine in adults and the elderly. Primary Objectives: * To describe the immunogenicity of the candidate vaccines after a single injection. * To describe the safety of the candidate vaccines after a single inj...

What is the current status of trial NCT00952276?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 548 participants. The study started on 2009-10. Estimated completion is 2011-03.

What interventions are being tested in trial NCT00952276?

The interventions under investigation include: Monovalent Subvirion A/H1N1 influenza vaccine with adjuvant (BIOLOGICAL), Monovalent Subvirion A/H1N1 influenza vaccine (BIOLOGICAL), Normal saline solution (BIOLOGICAL).

Who is sponsoring clinical trial NCT00952276?

This trial is sponsored by Sanofi, which has 713 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00952276's enrollment target sits among peer trials

548 62nd of 2000 higher than 1,939 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00952276, the US trial registry maintained by the National Library of Medicine. NCT00952276 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.