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NCT00906087 · ClinicalTrials.gov registry record · Phase 4

Effect of Myocilin Genetic Variants on Intraocular Pressure and Pressure Variation in Sitting and Supine Positions

A Phase 4 study, sponsored by University of Michigan.

Completed
Registry status
Phase 4
Development phase
14
Enrollment target

NCT00906087: Completed Phase 4 study, sponsored by University of Michigan.

NCT00906087 is a Phase 4 study that has completed, run by University of Michigan. The registered enrollment target is 14 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00906087, a Phase 4 study, has completed, sponsored by University of Michigan.

COMPLETED
Registry status
Phase 4
Development phase
14 participants
Enrollment target

Study Summary

The purpose of this study is to determine if one of the genes that can cause glaucoma, called myocilin, are associated with larger eye pressure and blood pressure changes in sitting and lying down positions without glaucoma drug treatment and with glaucoma drug treatment with a combination medication called Cosopt® (Merck \& Co., Inc.).

Primary Outcome

Effect of Cosopt treatment on intraocular pressure changes in sitting to supine positions.

Interventions

  • DRUG Cosopt (combination eyedrop of dorzolamide and timolol)

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2009-08-04
Est. Completion 2012-07-18
Phase Phase 4
University of Michigan

1,327 total trials

What the finished NCT00906087 record still lists

NCT00906087 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 1 intervention - of which Cosopt (combination eyedrop of dorzolamide and timolol) is the first listed.

NCT00906087 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00906087 about?

NCT00906087 is a clinical study titled "Effect of Myocilin Genetic Variants on Intraocular Pressure and Pressure Variation in Sitting and Supine Positions". The purpose of this study is to determine if one of the genes that can cause glaucoma, called myocilin, are associated with larger eye pressure and blood pressure changes in sitting and lying down positions without glaucoma drug treatment and with glaucoma drug treatment with a combination medicatio...

What is the current status of trial NCT00906087?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 14 participants. The study started on 2009-08-04. Estimated completion is 2012-07-18.

What interventions are being tested in trial NCT00906087?

The interventions under investigation include: Cosopt (combination eyedrop of dorzolamide and timolol) (DRUG).

Who is sponsoring clinical trial NCT00906087?

This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00906087's enrollment target sits among peer trials

14 1901st of 2000 higher than 91 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00906087, the US trial registry maintained by the National Library of Medicine. NCT00906087 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.