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NCT00892710 · ClinicalTrials.gov registry record · Phase 2
Trial of Poor Performance Status Patients (ToPPS)
A Phase 2 study of Non-Small Cell Lung Cancer, sponsored by SCRI Development Innovations.
- Completed
- Registry status
- Phase 2
- Development phase
- 172
- Enrollment target
- 20
- Study locations
NCT00892710: Completed Phase 2 study of Non-Small Cell Lung Cancer, sponsored by SCRI Development Innovations.
NCT00892710 is a Phase 2 study of Non-Small Cell Lung Cancer that has completed, run by SCRI Development Innovations. The registered enrollment target is 172 participants, below the 652-participant average among 454 other Non-Small Cell Lung Cancer trials with a reported enrollment target (74% lower). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00892710, a Phase 2 study of Non-Small Cell Lung Cancer, has completed, sponsored by SCRI Development Innovations.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 172 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this trial is to evaluate three treatment regimens in patients with stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) with a performance status of 2 and who were not previously treated.
Primary Outcome
The Length of Time, in Months, That Patients Were Alive From Their First Date of Protocol Treatment Until Worsening of Their Disease. Progression is defined using Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.0), as a 20% increase in the sum of the longest diameter of target lesions, or a measurable increase in a non-target lesion, or the appearance of new lesions.
Conditions Studied
Interventions
- DRUG Bevacizumab
- DRUG Carboplatin
- DRUG Pemetrexed
Study Locations (20)
Florida
- Aventura Medical Center - Aventura
- Collaborative Research Group/ Palm Beach Ins of Hem Onc - Boynton Beach
- Holy Cross Hospital - Fort Lauderdale
- Florida Cancer Specialists - Fort Myers
- Memorial Regional Cancer Center - Hollywood
- Watson Clinic Center for Cancer Care and Research - Lakeland
- Mount Sinai Comprehensive Cancer Center - Miami Beach
Arkansas
- Genesis Cancer Center - Hot Springs
- Northeast Arkansas Clinic - Jonesboro
Indiana
- Northern Indiana Cancer Research Consortium - South Bend
- RHHP/ Hope Cancer Center - Terra Haute
Ohio
- Oncology Hematology Care - Cincinnati
- Toledo Community Oncology Program - Toledo
Arizona
- Mayo Clinic - AZ - Scottsdale
California
- Wilshire Oncology Medical Group - LaVerne
Georgia
- Northeast Georgia Medical Center - Gainesville
Illinois
- University of Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 172 participants |
| Start Date | 2009-06 |
| Est. Completion | 2015-05 |
| Phase | Phase 2 |
What the finished NCT00892710 record still lists
NCT00892710 is an interventional study that assigns participants to a tested intervention. The registered 172 participants enrollment target is mid-sized for trials with a published cap, below the 652-participant average among 454 other Non-Small Cell Lung Cancer trials with a reported enrollment target (74% lower).
The record links to 1 condition, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 3 interventions - of which Bevacizumab is the first listed.
NCT00892710 names 20 study sites across 11 states, led by Florida, Arkansas, Indiana.
Frequently Asked Questions
What is clinical trial NCT00892710 about?
NCT00892710 is a clinical study titled "Trial of Poor Performance Status Patients (ToPPS)". The purpose of this trial is to evaluate three treatment regimens in patients with stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) with a performance status of 2 and who were not previously treated.
What is the current status of trial NCT00892710?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 172 participants. The study started on 2009-06. Estimated completion is 2015-05.
What conditions does trial NCT00892710 study?
This clinical trial studies the following conditions: Non-Small Cell Lung Cancer.
What interventions are being tested in trial NCT00892710?
The interventions under investigation include: Bevacizumab (DRUG), Carboplatin (DRUG), Pemetrexed (DRUG).
Who is sponsoring clinical trial NCT00892710?
This trial is sponsored by SCRI Development Innovations, which has 146 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00892710 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Non-Small Cell Lung Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00892710's enrollment target sits among peer trials
172 183rd of 454 higher than 272 of 454 other Non-Small Cell Lung Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Non-Small Cell Lung Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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