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Trial of Poor Performance Status Patients (ToPPS)
NCT00892710 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this trial is to evaluate three treatment regimens in patients with stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) with a performance status of 2 and who were not previously treated.
Conditions Studied
Interventions
- DRUG Bevacizumab
- DRUG Carboplatin
- DRUG Pemetrexed
Study Locations (20)
Florida
- Aventura Medical Center — Aventura
- Collaborative Research Group/ Palm Beach Ins of Hem Onc — Boynton Beach
- Holy Cross Hospital — Fort Lauderdale
- Florida Cancer Specialists — Fort Myers
- Memorial Regional Cancer Center — Hollywood
- Watson Clinic Center for Cancer Care and Research — Lakeland
- Mount Sinai Comprehensive Cancer Center — Miami Beach
Arkansas
- Genesis Cancer Center — Hot Springs
- Northeast Arkansas Clinic — Jonesboro
Indiana
- Northern Indiana Cancer Research Consortium — South Bend
- RHHP/ Hope Cancer Center — Terra Haute
Ohio
- Oncology Hematology Care — Cincinnati
- Toledo Community Oncology Program — Toledo
Arizona
- Mayo Clinic - AZ — Scottsdale
California
- Wilshire Oncology Medical Group — LaVerne
Georgia
- Northeast Georgia Medical Center — Gainesville
Illinois
- University of Chicago — Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 172 participants |
| Start Date | 2009-06 |
| Est. Completion | 2015-05 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00892710
The ClinicalTrials.gov registry entry for NCT00892710 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 172 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SCRI Development Innovations, which has 63 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Non Small Cell Lung Cancer appearing as the primary indexed condition, and to 3 interventions — of which Bevacizumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00892710 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Florida, Arkansas, Indiana. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00892710 about?
NCT00892710 is a clinical study titled "Trial of Poor Performance Status Patients (ToPPS)". The purpose of this trial is to evaluate three treatment regimens in patients with stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) with a performance status of 2 and who were not previously treated.
What is the current status of trial NCT00892710?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 172 participants. The study started on 2009-06. Estimated completion is 2015-05.
What conditions does trial NCT00892710 study?
This clinical trial studies the following conditions: Non Small Cell Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00892710?
The interventions under investigation include: Bevacizumab (DRUG), Carboplatin (DRUG), Pemetrexed (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00892710?
This trial is sponsored by SCRI Development Innovations, which has 63 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00892710 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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