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NCT00875745 · ClinicalTrials.gov registry record · Phase 1
Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)
A Phase 1 study of Myelodysplastic Syndromes and Leukemia, Myeloid, Acute, sponsored by Indiana University School of Medicine.
- Completed
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT00875745: Completed Phase 1 study of Myelodysplastic Syndromes and Leukemia, Myeloid, Acute, sponsored by Indiana University School of Medicine.
NCT00875745 is a Phase 1 study of Myelodysplastic Syndromes and Leukemia, Myeloid, Acute that has completed, run by Indiana University School of Medicine. The registered enrollment target is 15 participants, below the 285-participant average among 173 other Myelodysplastic Syndromes trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00875745, a Phase 1 study of Myelodysplastic Syndromes and Leukemia, Myeloid, Acute, has completed, sponsored by Indiana University School of Medicine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to test the safety of sorafenib and vorinostat when given together to see what effects (good and bad) it has on the patient and their acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). This study is also being done to find the highest dose of sorafenib and vorinostat that can be given together without causing severe side effects.
Conditions Studied
Interventions
- DRUG Sorafenib-Vorinostat
Study Locations (1)
Indiana
- Indiana University Melvin and Bren Simon Cancer Center - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2009-04 |
| Est. Completion | 2013-10 |
| Phase | Phase 1 |
What the finished NCT00875745 record still lists
NCT00875745 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 285-participant average among 173 other Myelodysplastic Syndromes trials with a reported enrollment target (95% lower).
The record links to 3 conditions, with Myelodysplastic Syndromes appearing as the primary indexed condition, and to 1 intervention - of which Sorafenib-Vorinostat is the first listed.
NCT00875745 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT00875745 about?
NCT00875745 is a clinical study titled "Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)". The purpose of this study is to test the safety of sorafenib and vorinostat when given together to see what effects (good and bad) it has on the patient and their acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). This study is also being done to find the highest dose of sorafenib and v...
What is the current status of trial NCT00875745?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2009-04. Estimated completion is 2013-10.
What conditions does trial NCT00875745 study?
This clinical trial studies the following conditions: Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Promyelocytic, Acute.
What interventions are being tested in trial NCT00875745?
The interventions under investigation include: Sorafenib-Vorinostat (DRUG).
Who is sponsoring clinical trial NCT00875745?
This trial is sponsored by Indiana University School of Medicine, which has 16 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00875745 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Myelodysplastic Syndromes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00875745's enrollment target sits among peer trials
15 150th of 173 higher than 21 of 173 other Myelodysplastic Syndromes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Myelodysplastic Syndromes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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