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NCT00868712 · ClinicalTrials.gov registry record
Warfarin and Coronary Calcification Project
A clinical trial of Coronary Calcification, sponsored by Walter Reed Army Medical Center.
- Completed
- Registry status
- 70
- Enrollment target
- 1
- Study location
NCT00868712: Completed study of Coronary Calcification, sponsored by Walter Reed Army Medical Center.
NCT00868712 is a study of Coronary Calcification that has completed, run by Walter Reed Army Medical Center. The registered enrollment target is 70 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00868712, a study of Coronary Calcification, has completed, sponsored by Walter Reed Army Medical Center.
- COMPLETED
- Registry status
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to assess whether the use of warfarin, a commonly used anticoagulation drug, is associated with increased amounts of coronary artery calcification. Studies in animals and preliminary but small retrospective studies in humans have suggested a possible link to increased tissue calcification with use of this drug. The researchers will investigate this by assessing the amount of calcification seen in the coronary arteries using a specialized computed tomography (CT) scan (electron-beam CT) and assessing to see if the amount is influenced by the amount of time a patient has been taking warfarin. The researchers will exclude patients with known coronary artery disease, chronic kidney disease or hyperparathyroidism.
Primary Outcome
The Agatston score is calculated using a non-contrast computed tomography (CT) scan to measure for the presence and severity of coronary artery disease through identification of calcification in the coronary arteries. Scores can range from 0 to several thousands. The measure is without units. Score categories are as follows: 0 = no coronary disease; 1-100 = low amount of coronary artery disease; 101-400 = moderately elevated score / moderate coronary artery disease; 401-1000 = severely elevated
Conditions Studied
Study Locations (1)
District of Columbia
- Walter Reed Army Medical Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2004-05 |
| Est. Completion | 2010-01 |
What the finished NCT00868712 record still lists
NCT00868712 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 70 participants, a relatively small participant target.
The record links to 1 condition, with Coronary Calcification appearing as the primary indexed condition, and to 0 interventions.
NCT00868712 reports a single indexed study location in District of Columbia.
Frequently Asked Questions
What is clinical trial NCT00868712 about?
NCT00868712 is a clinical study titled "Warfarin and Coronary Calcification Project". The purpose of the study is to assess whether the use of warfarin, a commonly used anticoagulation drug, is associated with increased amounts of coronary artery calcification. Studies in animals and preliminary but small retrospective studies in humans have suggested a possible link to increased tis...
What is the current status of trial NCT00868712?
This trial is currently completed. The enrollment target is 70 participants. The study started on 2004-05. Estimated completion is 2010-01.
What conditions does trial NCT00868712 study?
This clinical trial studies the following conditions: Coronary Calcification.
Who is sponsoring clinical trial NCT00868712?
This trial is sponsored by Walter Reed Army Medical Center, which has 24 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00868712 being conducted?
This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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